ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSEEREENGI SRATLNTQRL SAMIDSLNNE KDDRLFPSPT TTRTMITEEK ADQSDVFKPP 

        70         80         90        100        110        120 
SRLLRSPAGD VSLPPGDNRS SMISNYSGII QEGVEVSYVV KNRQQTQERR TSKDSNSLYS 

       130        140        150        160        170        180 
LKEPVSKNEL PSLPMLPSEA TLTKHLSDNQ STKSNTNADE IVIKPVTNAK PVGRFNSNTS 

       190        200        210        220        230        240 
KKVEGRGSLK LLSSPLRQEK VMRSSIGSGN LASESGSSTY NTKFHQSIQE QLEEEEEGNV 

       250        260        270        280        290        300 
SDKLSIVSSV IPELYTTTNE APKAINPIRS ETNDYNPTIP PRSKDRPRSR LFIEEGDGEG 

       310        320        330        340        350        360 
DLLTEEILPT PVQPGGHYKN SSQISTVSEQ KSESYYSAAT SMPPEEETYL TRPLPSTPNE 

       370        380        390        400        410        420 
DSRVTSNLKR DDTLKAIHDR ANHTSTSTNK QDDDMYEDII EETPKKTKLK KDTKKKLNKK 

       430        440        450        460        470        480 
KSVKELRSFD IDTLNQLLSV TKGTLIGSEF AQLGMKIEEK RALERLVDSL SRLTADMVLD 

       490        500 
PDRYEEGLKR LDKATKALEG F 

References and documentation are available.

Number of amino acids: 501

Molecular weight: 55923.30

Theoretical pI: 5.65

Amino acid composition: 
Ala (A)  19	  3.8%
Arg (R)  30	  6.0%
Asn (N)  29	  5.8%
Asp (D)  31	  6.2%
Cys (C)   0	  0.0%
Gln (Q)  17	  3.4%
Glu (E)  48	  9.6%
Gly (G)  22	  4.4%
His (H)   5	  1.0%
Ile (I)  24	  4.8%
Leu (L)  46	  9.2%
Lys (K)  42	  8.4%
Met (M)  10	  2.0%
Phe (F)   8	  1.6%
Pro (P)  31	  6.2%
Ser (S)  63	 12.6%
Thr (T)  42	  8.4%
Trp (W)   0	  0.0%
Tyr (Y)  12	  2.4%
Val (V)  22	  4.4%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 79
Total number of positively charged residues (Arg + Lys): 72

Atomic composition:

Carbon      C	      2400
Hydrogen    H	      3927
Nitrogen    N	       689
Oxygen      O	       823
Sulfur      S	        10

Formula: C2400H3927N689O823S10
Total number of atoms: 7849

Extinction coefficients:

This protein does not contain any Trp residues. Experience shows that
this could result in more than 10% error in the computed extinction coefficient.

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    17880
Abs 0.1% (=1 g/l)   0.320

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 56.64
This classifies the protein as unstable.



Aliphatic index: 71.02

Grand average of hydropathicity (GRAVY): -0.909