ProtParam
User-provided sequence:
10 20 30 40 50 60
MSELTEAEKR RLLRERRQKK FSNGGASSRL NKITGQASSH LNAESPLDAP SAAKTTPPAS
70 80 90 100 110 120
VHSATPDIKE DSNVAPQLDL LKQLAAMQGQ GTGKSTPQDS STPDLLSLLS SMNTGMPSAE
130 140 150 160 170 180
GTPSFGQAAP AAPINQAALD YHDYLLNRLK AWTILVKWVF FLLPYLYLIT RPNSSVWPAY
190 200 210 220 230 240
AFTQSAWFAP LRNPSNFTRI FATFEFLSIS IYYQLLKNVE HKSKIKNLQD TNKLVKLVSL
250 260 270 280
VPEGVIPVAN LKGKLITLLQ YWDLLSMLIT DISFVLIVLG LLTYL
References and
documentation are available.
Number of amino acids: 285
Molecular weight: 31493.39
Theoretical pI: 9.45
Total number of negatively charged residues (Asp + Glu): 21
Total number of positively charged residues (Arg + Lys): 28
Atomic composition:
Carbon C 1434
Hydrogen H 2275
Nitrogen N 373
Oxygen O 412
Sulfur S 5
Formula: C
1434H
2275N
373O
412S
5
Total number of atoms: 4499
Extinction coefficients:
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 40910
Abs 0.1% (=1 g/l) 1.299
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 43.41
This classifies the protein as unstable.
Aliphatic index: 100.35
Grand average of hydropathicity (GRAVY): -0.055