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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSEPSKEELL ARIAQLELEN EQLKQQNGKK SQHEQFNKID DNFSLDEYKR YGRQMIVPQF

70 80 90 100 110 120
GSLESQIKLK NSKVLVVGAG GLGSPALLYL SSAGIGKIGI IDPDTVDTSN LHRQVIHNTE

130 140 150 160 170 180
MVGEFKCISA QNYINKLNPH VVVEVYPTAL NNDNAFGIVS QYDLVLDCTD HPAVRYLIND

190 200 210 220 230 240
VCVLLGKTIV SGSGLKSDGQ LTVLNFANSG PCYRCFYPQP PSPDSVTSCS DGGVIGPAIG

250 260 270 280 290 300
LVGVAMAVET IKIITGYYTK DNFVPFLASY SAYPQQQLRV FKMRKRQKDC AVCGENPQIS

310 320 330 340 350 360
QRMIEDGTIN YKTFCGRATF DPIDDKFRVS PKDYDSVVQN KKKHILIDVR PREQFQITHL

370 380 390 400 410 420
PNAINVQWDP TFRKADAIEQ YLPDDSTKDD EIYVVCRFGN DSQLAAKKLI GMGYPNVRDI

430
IGGLDKWSDD VDSKIPKY


References and documentation are available.

Number of amino acids: 438 Molecular weight: 48866.60 Theoretical pI: 6.03
Amino acid composition: 
Ala (A) 22 5.0% Arg (R) 17 3.9% Asn (N) 24 5.5% Asp (D) 35 8.0% Cys (C) 10 2.3% Gln (Q) 26 5.9% Glu (E) 18 4.1% Gly (G) 31 7.1% His (H) 7 1.6% Ile (I) 33 7.5% Leu (L) 33 7.5% Lys (K) 32 7.3% Met (M) 7 1.6% Phe (F) 16 3.7% Pro (P) 24 5.5% Ser (S) 30 6.8% Thr (T) 17 3.9% Trp (W) 2 0.5% Tyr (Y) 19 4.3% Val (V) 35 8.0% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 53 Total number of positively charged residues (Arg + Lys): 49 Atomic composition: Carbon C 2171 Hydrogen H 3421 Nitrogen N 587 Oxygen O 661 Sulfur S 17 Formula: C2171H3421N587O661S17 Total number of atoms: 6857 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 39935 Abs 0.1% (=1 g/l) 0.817, assuming all pairs of Cys residues form cystines Ext. coefficient 39310 Abs 0.1% (=1 g/l) 0.804, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 35.62 This classifies the protein as stable. Aliphatic index: 86.96 Grand average of hydropathicity (GRAVY): -0.351