ProtParam
User-provided sequence:
10 20 30 40 50 60
MSERESLNSQ LEHLQMRYVG TGHADISKHE WLTNQHRDSL SSFIGHSSFL SLFSIAENES
70 80 90
VGRVRYNTLT KMISPCGPAP KIKDNTMDKE EKND
References and
documentation are available.
Number of amino acids: 94
Molecular weight: 10708.95
Theoretical pI: 6.18
Total number of negatively charged residues (Asp + Glu): 13
Total number of positively charged residues (Arg + Lys): 11
Atomic composition:
Carbon C 460
Hydrogen H 727
Nitrogen N 135
Oxygen O 150
Sulfur S 5
Formula: C
460H
727N
135O
150S
5
Total number of atoms: 1477
Extinction coefficients:
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 8480
Abs 0.1% (=1 g/l) 0.792, assuming all pairs of Cys residues form cystines
Ext. coefficient 8480
Abs 0.1% (=1 g/l) 0.792, assuming all Cys residues are reduced
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 32.36
This classifies the protein as stable.
Aliphatic index: 66.38
Grand average of hydropathicity (GRAVY): -0.784