ProtParam
User-provided sequence:
10 20 30 40 50 60
MSERESWHKE IDLFFVAMGY FTRIPMPKWV EVDADKLNKA SRYFGLVGLL VGLLSAIIFW
70 80 90 100 110 120
LTQNWLPAGV SVLLSMLTGI LLTGGFHEDG LADTFDGFGG GWTAEDKLRI MKDSRLGSYG
130 140 150 160 170 180
ALALIMVLLL KWQLLVELAL YDPVVAGSAM IVAHTVSRVV AASLIFTETY VRDDETSKSK
190 200 210 220 230 240
PLAQHQGIND LFILIASGVL VLLVLKGIAA LSLLLVMIGL RRLIVVIFRR QIGGYTGDTL
250 260
GAAQQICEIV CYFVLLVVGG IL
References and
documentation are available.
Number of amino acids: 262
Molecular weight: 28675.04
Theoretical pI: 6.08
Total number of negatively charged residues (Asp + Glu): 23
Total number of positively charged residues (Arg + Lys): 21
Atomic composition:
Carbon C 1329
Hydrogen H 2119
Nitrogen N 329
Oxygen O 353
Sulfur S 10
Formula: C
1329H
2119N
329O
353S
10
Total number of atoms: 4140
Extinction coefficients:
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 43555
Abs 0.1% (=1 g/l) 1.519, assuming all pairs of Cys residues form cystines
Ext. coefficient 43430
Abs 0.1% (=1 g/l) 1.515, assuming all Cys residues are reduced
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 27.49
This classifies the protein as stable.
Aliphatic index: 132.06
Grand average of hydropathicity (GRAVY): 0.717