ProtParam
User-provided sequence:
10 20 30 40 50 60
MSESSDISAM QPVNPKPFLK GLVNHRVGVK LKFNSTEYRG TLVSTDNYFN LQLNEAEEFV
70 80
AGVSHGTLGE IFIRCNNVLY IRELPN
References and
documentation are available.
Number of amino acids: 86
Molecular weight: 9659.98
Theoretical pI: 6.06
Total number of negatively charged residues (Asp + Glu): 9
Total number of positively charged residues (Arg + Lys): 8
Atomic composition:
Carbon C 430
Hydrogen H 675
Nitrogen N 117
Oxygen O 130
Sulfur S 3
Formula: C
430H
675N
117O
130S
3
Total number of atoms: 1355
Extinction coefficients:
This protein does not contain any Trp residues. Experience shows that
this could result in more than 10% error in the computed extinction coefficient.
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 4470
Abs 0.1% (=1 g/l) 0.463, assuming all pairs of Cys residues form cystines
Ext. coefficient 4470
Abs 0.1% (=1 g/l) 0.463, assuming all Cys residues are reduced
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 28.36
This classifies the protein as stable.
Aliphatic index: 89.42
Grand average of hydropathicity (GRAVY): -0.228