ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSETDRERPL LASEERAYEE TEKVLIVGID EEEDADYDDD PGNSPKFSWK KLWLFTGPGF 

        70         80         90        100        110        120 
LMSIAFLDPG NLESDLQAGA IAGYSLIWLL MWATAIGLLI QLLSARLGVA TGRHLAELCR 

       130        140        150        160        170        180 
EEYPTWARMV LWIMAEIALI GADIQEVIGS AIAIKILSNG LVPLWAGVVI TALDCFIFLF 

       190        200        210        220        230        240 
LENYGIRKLE AVFAILIATM ALAFAWMFGQ TKPSGTELLV GALVPKLSSR TIKQAVGIVG 

       250        260        270        280        290        300 
CIIMPHNVFL HSALVQSREV DPKKRFRVKE ALKYYSIEST GALAVSFIIN VFVTTVFAKS 

       310        320        330        340        350        360 
FYGTEIADTI GLANAGQYLQ DKYGGGFFPI LYIWAIGVLA AGQSSTITGT YAGQFIMGGF 

       370        380        390        400        410        420 
LNLKMKKWVR ALITRSCAII PTMIVALVFD SSDSMLDELN EWLNVLQSVQ IPFAVIPLLC 

       430        440        450        460        470        480 
LVSNEQIMGS FKIQPLVQTI SWIVAALVIA INGYLMVDFF SGAATNLILL VPVIIFAIAY 

       490        500        510 
VVFVLYLISR GLTYTPWQLV ASSHKEPQRD DE 

References and documentation are available.

Number of amino acids: 512

Molecular weight: 56385.17

Theoretical pI: 4.99

Amino acid composition: 
Ala (A)  52	 10.2%
Arg (R)  16	  3.1%
Asn (N)  13	  2.5%
Asp (D)  20	  3.9%
Cys (C)   5	  1.0%
Gln (Q)  17	  3.3%
Glu (E)  28	  5.5%
Gly (G)  37	  7.2%
His (H)   4	  0.8%
Ile (I)  51	 10.0%
Leu (L)  63	 12.3%
Lys (K)  20	  3.9%
Met (M)  14	  2.7%
Phe (F)  27	  5.3%
Pro (P)  19	  3.7%
Ser (S)  33	  6.4%
Thr (T)  25	  4.9%
Trp (W)  13	  2.5%
Tyr (Y)  16	  3.1%
Val (V)  39	  7.6%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 48
Total number of positively charged residues (Arg + Lys): 36

Atomic composition:

Carbon      C	      2615
Hydrogen    H	      4089
Nitrogen    N	       631
Oxygen      O	       713
Sulfur      S	        19

Formula: C2615H4089N631O713S19
Total number of atoms: 8067

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    95590
Abs 0.1% (=1 g/l)   1.695, assuming all pairs of Cys residues form cystines


Ext. coefficient    95340
Abs 0.1% (=1 g/l)   1.691, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 33.89
This classifies the protein as stable.



Aliphatic index: 119.08

Grand average of hydropathicity (GRAVY): 0.554