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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSEVSKWPAI NPFHWGYNGT VSHIVGENGS IKLHLKDNKE QVDFDEFANK YVPTLKNGAQ

70 80 90 100 110 120
FKLSPYLFTG ILQTLYLGAA DFSKKFPVFY GREIVKFSDG GVCTADWLID SWKKDYEFDQ

130 140 150 160 170 180
STTSFDKKKF DKDEKATHPE GWPRLQPRTR YLKDNELEEL REVDLPLVVI LHGLAGGSHE

190 200 210 220 230 240
PIIRSLAENL SRSGRFQVVV LNTRGCARSK ITTRNLFTAY HTMDIREFLQ REKQRHPDRK

250 260 270 280 290 300
LYAVGCSFGA TMLANYLGEE GDKSPLSAAA TLCNPWDLLL SAIRMSQDWW SRTLFSKNIA

310 320 330 340 350 360
QFLTRTVQVN MGELGVPNGS LPDHPPTVKN PSFYMFTPEN LIKAKSFKST REFDEVYTAP

370 380 390 400 410 420
ALGFPNAMEY YKAASSINRV DTIRVPTLVI NSRDDPVVGP DQPYSIVEKN PRILYCRTDL

430 440 450
GGHLAYLDKD NNSWATKAIA EFFTKFDELV V


References and documentation are available.

Number of amino acids: 451 Molecular weight: 51255.25 Theoretical pI: 7.64
Amino acid composition: 
Ala (A) 29 6.4% Arg (R) 24 5.3% Asn (N) 23 5.1% Asp (D) 29 6.4% Cys (C) 5 1.1% Gln (Q) 12 2.7% Glu (E) 26 5.8% Gly (G) 27 6.0% His (H) 10 2.2% Ile (I) 20 4.4% Leu (L) 42 9.3% Lys (K) 32 7.1% Met (M) 7 1.6% Phe (F) 26 5.8% Pro (P) 26 5.8% Ser (S) 31 6.9% Thr (T) 28 6.2% Trp (W) 9 2.0% Tyr (Y) 17 3.8% Val (V) 28 6.2% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 55 Total number of positively charged residues (Arg + Lys): 56 Atomic composition: Carbon C 2318 Hydrogen H 3563 Nitrogen N 619 Oxygen O 673 Sulfur S 12 Formula: C2318H3563N619O673S12 Total number of atoms: 7185 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 75080 Abs 0.1% (=1 g/l) 1.465, assuming all pairs of Cys residues form cystines Ext. coefficient 74830 Abs 0.1% (=1 g/l) 1.460, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 32.91 This classifies the protein as stable. Aliphatic index: 78.05 Grand average of hydropathicity (GRAVY): -0.419