ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSFDWLNVPG LDLSSGDQAE KRPSNGLGPP SVSFDFGINT AAPHDSSFWD QGSRSHSDTT 

        70         80         90        100        110        120 
LSYRNNHSNT AADNATNVSS PQKDNPPNGE VRTLSGGDVY AESPEDMQVP LSLSQNQLTH 

       130        140        150        160        170        180 
EEIRTYLRWY HYICLRTHGK LVRLNDVFRF LTNFNLSQKV KDRIVEIFRS CKNALNIGQF 

       190        200        210        220        230        240 
FAVLRLVSRA IIYGILPLRR MILEKAPVPK PRPILSSENH EEVYEEVEDD DSSAKTGDQK 

       250        260        270        280        290        300 
VDFDSFASLL LTGKTTRKRV RRRIKNLNFK SKKVRFSEHI TFQDPPNLNQ ESSNNSEARK 

       310        320        330        340        350        360 
QDPDAEDEDQ DSNNDSPLDF TLPMDQLLKR LYKRRKNSGL VSSLPSEQQE TEEEKKVLED 

       370        380        390        400        410        420 
MKDSLSHFKQ IQTVDSASLP ISSVFLQNGN TLPTSNVNNT TVPQQLPLEP LKPTATGSAN 

       430        440        450        460        470        480 
HLVREEYNQG LHPSNGAIQT GLQPLKPTAT GSANYLMRSH MEQPQSIKPS STPETVTNSG 

       490        500        510        520        530        540 
GLQPLKPTAT GSANYLMKQH ISPSVNNPVS SMFQAQFTNQ SSSPQSTGPA FLNSPNITLP 

       550        560        570        580        590        600 
QSNQQQPYQE VNPTQAKIEP SNISPQHTYS NNVRINNGNI VSMPKVEITG AFPPQNTLPQ 

       610        620        630        640        650        660 
HQQSHLLSPQ NTIPQHQRSQ LISPQNTFTQ NQPILSPQHT YSNNQATMIS PQNTYTNNQQ 

       670        680        690        700        710        720 
QPQHLPPPPP PRAQQQQQGA IVPPQHMYSN VQKQNNLVPT QPSYTNSPSI QSPNFLSPQN 

       730        740        750        760        770        780 
AANSYFQSLL SSSPSPNPTP SNASTVNGNN ASNGISSFQN TSAAMNNTQS HQTYIQQQQQ 

       790        800        810        820        830        840 
QQTQQRIYGG QLSQMQQHPG QLHLNNSDIH SQPNKPNYGM LGQQVHQQQQ QQQQQFPFTA 

       850        860        870 
DVNRSNSSDI LGNLQSLQQQ VDALQIQYNR RP 

References and documentation are available.

Number of amino acids: 872

Molecular weight: 97305.38

Theoretical pI: 7.42

Amino acid composition: 
Ala (A)  38	  4.4%
Arg (R)  35	  4.0%
Asn (N)  83	  9.5%
Asp (D)  35	  4.0%
Cys (C)   2	  0.2%
Gln (Q) 104	 11.9%
Glu (E)  33	  3.8%
Gly (G)  36	  4.1%
His (H)  25	  2.9%
Ile (I)  36	  4.1%
Leu (L)  70	  8.0%
Lys (K)  33	  3.8%
Met (M)  15	  1.7%
Phe (F)  28	  3.2%
Pro (P)  78	  8.9%
Ser (S) 102	 11.7%
Thr (T)  55	  6.3%
Trp (W)   3	  0.3%
Tyr (Y)  22	  2.5%
Val (V)  39	  4.5%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 68
Total number of positively charged residues (Arg + Lys): 68

Atomic composition:

Carbon      C	      4212
Hydrogen    H	      6610
Nitrogen    N	      1250
Oxygen      O	      1375
Sulfur      S	        17

Formula: C4212H6610N1250O1375S17
Total number of atoms: 13464

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    49405
Abs 0.1% (=1 g/l)   0.508, assuming all pairs of Cys residues form cystines


Ext. coefficient    49280
Abs 0.1% (=1 g/l)   0.506, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 67.55
This classifies the protein as unstable.



Aliphatic index: 64.74

Grand average of hydropathicity (GRAVY): -0.891