ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSFFNFKAFG RNSKKNKNQP LNVAQPPAMN TIYSSPHSSN SRLSLRNKHH SPKRHSQTSF 

        70         80         90        100        110        120 
PAQKSTPQSQ QLTSTTPQSQ QQEASERSES QQIMFLSEPF VRTALVKGSF KTIVQLPKYV 

       130        140        150        160        170        180 
DLGEWIALNV FEFFTNLNQF YGVVAEYVTP DAYPTMNAGP HTDYLWLDAN NRQVSLPASQ 

       190        200        210        220        230        240 
YIDLALTWIN NKVNDKNLFP TKNGLPFPQQ FSRDVQRIMV QMFRIFAHIY HHHFDKIVHL 

       250        260        270        280 
SLEAHWNSFF SHFISFAKEF KIIDRKEMAP LLPLIESFEK QGKIIYN 

References and documentation are available.

Number of amino acids: 287

Molecular weight: 33275.84

Theoretical pI: 9.60

Amino acid composition: 
Ala (A)  17	  5.9%
Arg (R)  11	  3.8%
Asn (N)  21	  7.3%
Asp (D)   9	  3.1%
Cys (C)   0	  0.0%
Gln (Q)  22	  7.7%
Glu (E)  12	  4.2%
Gly (G)   7	  2.4%
His (H)  12	  4.2%
Ile (I)  16	  5.6%
Leu (L)  22	  7.7%
Lys (K)  19	  6.6%
Met (M)   7	  2.4%
Phe (F)  24	  8.4%
Pro (P)  19	  6.6%
Ser (S)  28	  9.8%
Thr (T)  14	  4.9%
Trp (W)   4	  1.4%
Tyr (Y)   9	  3.1%
Val (V)  14	  4.9%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 21
Total number of positively charged residues (Arg + Lys): 30

Atomic composition:

Carbon      C	      1516
Hydrogen    H	      2298
Nitrogen    N	       410
Oxygen      O	       424
Sulfur      S	         7

Formula: C1516H2298N410O424S7
Total number of atoms: 4655

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    35410
Abs 0.1% (=1 g/l)   1.064

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 48.21
This classifies the protein as unstable.



Aliphatic index: 71.71

Grand average of hydropathicity (GRAVY): -0.492