ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSFQDLESGR GRSTRKFNGG RQDSTQAVAS GIFQINTGVS TFQRLVNTLG TPKDTPELRE 

        70         80         90        100        110        120 
KLHKTRLHIG QLVKDTSAKL KEASETDHQS GVNPSKKIAD AKLARDFQAV LKEFQKAQQT 

       130        140        150        160        170        180 
AAERETTYTP FVPQSALPSS YTAGEVDKVP EQRAQLQESK RQELVLLDNE IAFNEAVIEE 

       190        200        210        220        230        240 
REQGIQEIHQ QIGEVNEIFK DLAVLVNDQG VMIDDIGTHI DNSRAATSQG KSQLVQAAKT 

       250        260 
QKSNSSLTCL LLVIFGIVLL IVIIVLAA 

References and documentation are available.

Number of amino acids: 268

Molecular weight: 29481.32

Theoretical pI: 6.01

Amino acid composition: 
Ala (A)  23	  8.6%
Arg (R)  13	  4.9%
Asn (N)  10	  3.7%
Asp (D)  14	  5.2%
Cys (C)   1	  0.4%
Gln (Q)  25	  9.3%
Glu (E)  20	  7.5%
Gly (G)  16	  6.0%
His (H)   5	  1.9%
Ile (I)  18	  6.7%
Leu (L)  25	  9.3%
Lys (K)  18	  6.7%
Met (M)   2	  0.7%
Phe (F)  10	  3.7%
Pro (P)   7	  2.6%
Ser (S)  20	  7.5%
Thr (T)  19	  7.1%
Trp (W)   0	  0.0%
Tyr (Y)   2	  0.7%
Val (V)  20	  7.5%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 34
Total number of positively charged residues (Arg + Lys): 31

Atomic composition:

Carbon      C	      1288
Hydrogen    H	      2108
Nitrogen    N	       370
Oxygen      O	       413
Sulfur      S	         3

Formula: C1288H2108N370O413S3
Total number of atoms: 4182

Extinction coefficients:

This protein does not contain any Trp residues. Experience shows that
this could result in more than 10% error in the computed extinction coefficient.

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient     2980
Abs 0.1% (=1 g/l)   0.101, assuming all pairs of Cys residues form cystines


Ext. coefficient     2980
Abs 0.1% (=1 g/l)   0.101, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 39.62
This classifies the protein as stable.



Aliphatic index: 92.80

Grand average of hydropathicity (GRAVY): -0.373