ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSFRRRSSSS SSEAENRRDP AMAEVEKPTA ATPPTDIPQA TAAPASEAPV AVTPTADTTV 

        70         80         90        100        110        120 
DVEPGTSPTQ EPNSNSHPHD SEYDTASDLE GGEDYDDEES ASGSASGSGS EEESETDDED 

       130        140        150        160        170        180 
DEVGSETDDG EGEQAMDRSV ADSEAQKKVD EDRSNPQYIP KRGTFYEHDD RTAETEGEIL 

       190        200        210        220        230        240 
IEPENGAGQA AAEPNGELNG LAAAGATPTG QTPQISQASK TMRKWQPASG GDRWSHDRFE 

       250        260        270        280        290        300 
ATEQAPKSRA ELLQTYGYDI RNEDAPPRAR RRRRYTRGPS KYSRNWEDEQ AYLKASNKER 

       310        320        330        340        350        360 
KPPRPQDFPA LNERKPRGPR TSSSREEKEN RRSVAAEGLV PEKQQPLASS SNPHRSQERE 

       370        380        390        400        410        420 
RERERERERD REPKNRNFGR MNGGPGRQNG MEFKKNNRGQ QLRERERGPD QLDNRNQKPS 

       430        440        450        460        470        480 
TPRSNQQQQP QQQPHHQQQP QQQRQPSQPQ QSPQTPLSTS NLSQRLQQVQ QRNDPSHVGS 

       490        500        510        520        530        540 
VQMHSLASQN QAPQQQQQQP LHQEQRNAPK RYSSLRRSQQ EASQHLAEQQ QQQMQQQLHL 

       550        560        570        580        590        600 
QQQQQQQQSQ IMIQDPHVLM QIAYQQQELQ AQLQTMQLGP PTAAGAVPTP PKPHAPPAAA 

       610        620        630        640        650        660 
YPQAQAAPYY VTGTEPVPVP VPQAPYVNPA SAAYLPTTPA AVAYAQAGPP VVTQPTPPPA 

       670        680        690        700        710        720 
QAPPATQPAQ PYQNYNTVGG TTYFVPPAQT TSRPSALPQR RPTNAIPILP PSEKHKVKGG 

       730        740        750        760        770        780 
AKEEGISDNI DHIIDNMFVQ RPSAFQATGE GATPGGGTKE EAAATPPAAE QNLQPVPATG 


QE 

References and documentation are available.

Number of amino acids: 782

Molecular weight: 86065.28

Theoretical pI: 5.44

Amino acid composition: 
Ala (A)  83	 10.6%
Arg (R)  58	  7.4%
Asn (N)  33	  4.2%
Asp (D)  36	  4.6%
Cys (C)   0	  0.0%
Gln (Q) 101	 12.9%
Glu (E)  67	  8.6%
Gly (G)  46	  5.9%
His (H)  16	  2.0%
Ile (I)  15	  1.9%
Leu (L)  29	  3.7%
Lys (K)  25	  3.2%
Met (M)  12	  1.5%
Phe (F)   9	  1.2%
Pro (P)  91	 11.6%
Ser (S)  62	  7.9%
Thr (T)  48	  6.1%
Trp (W)   3	  0.4%
Tyr (Y)  20	  2.6%
Val (V)  28	  3.6%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 103
Total number of positively charged residues (Arg + Lys): 83

Atomic composition:

Carbon      C	      3642
Hydrogen    H	      5736
Nitrogen    N	      1150
Oxygen      O	      1253
Sulfur      S	        12

Formula: C3642H5736N1150O1253S12
Total number of atoms: 11793

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    46300
Abs 0.1% (=1 g/l)   0.538

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 75.49
This classifies the protein as unstable.



Aliphatic index: 42.94

Grand average of hydropathicity (GRAVY): -1.307