ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSFSHSFIFI VIFCMQSLAA LLQNGFMATV LGREWVRSQG LPAGDMIMAC LAASRFCLHG 

        70         80         90        100        110        120 
IAVLNNFLAS AMFWTIKNYF SILWDFTNTV NFWFTTWLAI FYCVKISSFS HPIFFWIKWR 

       130        140        150        160        170        180 
ISRSVPRLLL GSLIIGGLSA ISSATGNTIA LQMAACENYT IYYKMMAFYL YYFRCHAMLM 

       190        200        210        220        230        240 
WVIPFFLFLL SIILLMFSLY RHLEQMRYHR PRTHDYSTQA HIMALKSLAF FLIFYTSYTL 

       250        260        270        280        290 
LLTVSVAHVI NVHGSWHWAW EVVTYMGISL HSTILILSNT KMRKALKIKF PDLCIPRS 

References and documentation are available.

Number of amino acids: 298

Molecular weight: 34628.28

Theoretical pI: 9.66

Amino acid composition: 
Ala (A)  24	  8.1%
Arg (R)  13	  4.4%
Asn (N)  10	  3.4%
Asp (D)   4	  1.3%
Cys (C)   7	  2.3%
Gln (Q)   6	  2.0%
Glu (E)   4	  1.3%
Gly (G)  11	  3.7%
His (H)  12	  4.0%
Ile (I)  28	  9.4%
Leu (L)  37	 12.4%
Lys (K)   9	  3.0%
Met (M)  16	  5.4%
Phe (F)  26	  8.7%
Pro (P)   7	  2.3%
Ser (S)  28	  9.4%
Thr (T)  17	  5.7%
Trp (W)  11	  3.7%
Tyr (Y)  14	  4.7%
Val (V)  14	  4.7%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 8
Total number of positively charged residues (Arg + Lys): 22

Atomic composition:

Carbon      C	      1633
Hydrogen    H	      2457
Nitrogen    N	       397
Oxygen      O	       390
Sulfur      S	        23

Formula: C1633H2457N397O390S23
Total number of atoms: 4900

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    81735
Abs 0.1% (=1 g/l)   2.360, assuming all pairs of Cys residues form cystines


Ext. coefficient    81360
Abs 0.1% (=1 g/l)   2.350, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 35.88
This classifies the protein as stable.



Aliphatic index: 106.74

Grand average of hydropathicity (GRAVY): 0.655