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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSFSVEKKTT LAHPFRAPGS TLISSDQSNL KIVYNKYKTR SPLPNSTNQL RYNFIFCHGT

70 80 90 100 110 120
GFNKSIWKYH ISKLYQLSQS LQVPWFLDSV IAIDMVGHGD SSLENQGKLG TIFRWDDGAK

130 140 150 160 170 180
DVIAIIKHEI ATTGDFQNNL ESRNLIIGHS MGGFNSLYAT FLEPSLFDAV IPIEAVIYGA

190 200 210 220 230 240
PGGLEKFSKK FSKISKLLID TFDSKDDINF FFKEFSFFKN MQDQVSDDFI NDEVYEIKDK

250 260 270 280 290 300
ESGEIKYKLK CNTPHQMAAY YGAFMSIPFG MFAIPHIRVP ICHVIGSKGV WNPPESITWI

310 320 330 340 350 360
RGAINKEFLA GKVDVPKGEH LLNVELPDET IDIIQNFTTE RTKAFIEARN NLPEVKLNNN

370 380 390 400
KEAIAKEQFQ NLIDLKFDQV NGYFIEDRVD NYEALQKLAK L


References and documentation are available.

Number of amino acids: 401 Molecular weight: 45631.10 Theoretical pI: 6.23
Amino acid composition: 
Ala (A) 22 5.5% Arg (R) 10 2.5% Asn (N) 27 6.7% Asp (D) 25 6.2% Cys (C) 3 0.7% Gln (Q) 15 3.7% Glu (E) 24 6.0% Gly (G) 24 6.0% His (H) 10 2.5% Ile (I) 38 9.5% Leu (L) 31 7.7% Lys (K) 35 8.7% Met (M) 7 1.7% Phe (F) 30 7.5% Pro (P) 17 4.2% Ser (S) 29 7.2% Thr (T) 17 4.2% Trp (W) 5 1.2% Tyr (Y) 13 3.2% Val (V) 19 4.7% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 49 Total number of positively charged residues (Arg + Lys): 45 Atomic composition: Carbon C 2082 Hydrogen H 3197 Nitrogen N 533 Oxygen O 601 Sulfur S 10 Formula: C2082H3197N533O601S10 Total number of atoms: 6423 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 46995 Abs 0.1% (=1 g/l) 1.030, assuming all pairs of Cys residues form cystines Ext. coefficient 46870 Abs 0.1% (=1 g/l) 1.027, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 32.87 This classifies the protein as stable. Aliphatic index: 86.33 Grand average of hydropathicity (GRAVY): -0.280