ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSGENRAVVP IESNPEVFTN FAHKLGLKNE WAYFDIYSLT EPELLAFLPR PVKAIVLLFP 

        70         80         90        100        110        120 
INEDRKSSTS QQITSSYDVI WFKQSVKNAC GLYAILHSLS NNQSLLEPGS DLDNFLKSQS 

       130        140        150        160        170        180 
DTSSSKNRFD DVTTDQFVLN VIKENVQTFS TGQSEAPEAT ADTNLHYITY VEENGGIFEL 

       190        200        210        220        230 
DGRNLSGPLY LGKSDPTATD LIEQELVRVR VASYMENANE EDVLNFAMLG LGPNWE 

References and documentation are available.

Number of amino acids: 236

Molecular weight: 26385.37

Theoretical pI: 4.45

Amino acid composition: 
Ala (A)  14	  5.9%
Arg (R)   7	  3.0%
Asn (N)  19	  8.1%
Asp (D)  14	  5.9%
Cys (C)   1	  0.4%
Gln (Q)   9	  3.8%
Glu (E)  20	  8.5%
Gly (G)  12	  5.1%
His (H)   3	  1.3%
Ile (I)  11	  4.7%
Leu (L)  26	 11.0%
Lys (K)  10	  4.2%
Met (M)   3	  1.3%
Phe (F)  12	  5.1%
Pro (P)  11	  4.7%
Ser (S)  23	  9.7%
Thr (T)  14	  5.9%
Trp (W)   3	  1.3%
Tyr (Y)   8	  3.4%
Val (V)  16	  6.8%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 34
Total number of positively charged residues (Arg + Lys): 17

Atomic composition:

Carbon      C	      1176
Hydrogen    H	      1812
Nitrogen    N	       304
Oxygen      O	       378
Sulfur      S	         4

Formula: C1176H1812N304O378S4
Total number of atoms: 3674

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    28420
Abs 0.1% (=1 g/l)   1.077, assuming all pairs of Cys residues form cystines


Ext. coefficient    28420
Abs 0.1% (=1 g/l)   1.077, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 45.58
This classifies the protein as unstable.



Aliphatic index: 86.74

Grand average of hydropathicity (GRAVY): -0.332