ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSGFRAFKAQ VPIEWSQSLY ITLVRGLPGT RKLHRRTLEA MGLRRCHRTV LHSNNSSIRG 

        70         80         90        100 
MIDQVKRMVV VETEEMYNAR KEAEANHKAL RPPLVVSHSS PATDSSNMS 

References and documentation are available.

Number of amino acids: 109

Molecular weight: 12359.26

Theoretical pI: 10.59

Amino acid composition: 
Ala (A)   8	  7.3%
Arg (R)  12	 11.0%
Asn (N)   5	  4.6%
Asp (D)   2	  1.8%
Cys (C)   1	  0.9%
Gln (Q)   3	  2.8%
Glu (E)   7	  6.4%
Gly (G)   5	  4.6%
His (H)   5	  4.6%
Ile (I)   4	  3.7%
Leu (L)   9	  8.3%
Lys (K)   5	  4.6%
Met (M)   6	  5.5%
Phe (F)   2	  1.8%
Pro (P)   5	  4.6%
Ser (S)  12	 11.0%
Thr (T)   6	  5.5%
Trp (W)   1	  0.9%
Tyr (Y)   2	  1.8%
Val (V)   9	  8.3%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 9
Total number of positively charged residues (Arg + Lys): 17

Atomic composition:

Carbon      C	       532
Hydrogen    H	       875
Nitrogen    N	       169
Oxygen      O	       156
Sulfur      S	         7

Formula: C532H875N169O156S7
Total number of atoms: 1739

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient     8480
Abs 0.1% (=1 g/l)   0.686, assuming all pairs of Cys residues form cystines


Ext. coefficient     8480
Abs 0.1% (=1 g/l)   0.686, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 69.34
This classifies the protein as unstable.



Aliphatic index: 77.80

Grand average of hydropathicity (GRAVY): -0.481