ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSGIIDASSA LRKRKHLKRG ITFTVMIVGQ SGSGRSTFIN TLCGQQVVDT STTILLPTDT 

        70         80         90        100        110        120 
STEIDLQLRE ETVELEDDEG VKIQLNIIDT PGFGDSLDNS PSFEIISDYI RHQYDEILLE 

       130        140        150        160        170        180 
ESRVRRNPRF KDGRVHCCLY LINPTGHGLK EIDVEFIRQL GSLVNIIPVI SKSDSLTRDE 

       190        200        210        220        230        240 
LKLNKKLIME DIDRWNLPIY NFPFDEDEIS DEDYETNMYL RTLLPFAIIG SNEVYEMGGD 

       250        260        270        280        290        300 
VGTIRGRKYP WGILDVEDSS ISDFVILRNA LLISHLHDLK NYTHEILYER YRTEALSGES 

       310        320        330        340        350        360 
VAAESIRPNL TKLNGSSSSS TTTRRNTNPF KQSNNINNDV LNPASDMHGQ STGENNETYM 

       370        380        390        400        410 
TREEQIRLEE ERLKAFEERV QQELLLKRQE LLQREKELRE IEARLEKEAK IKQEE 

References and documentation are available.

Number of amino acids: 415

Molecular weight: 47648.52

Theoretical pI: 4.92

Amino acid composition: 
Ala (A)  11	  2.7%
Arg (R)  31	  7.5%
Asn (N)  24	  5.8%
Asp (D)  28	  6.7%
Cys (C)   3	  0.7%
Gln (Q)  15	  3.6%
Glu (E)  45	 10.8%
Gly (G)  23	  5.5%
His (H)   8	  1.9%
Ile (I)  37	  8.9%
Leu (L)  45	 10.8%
Lys (K)  20	  4.8%
Met (M)   7	  1.7%
Phe (F)  12	  2.9%
Pro (P)  13	  3.1%
Ser (S)  34	  8.2%
Thr (T)  27	  6.5%
Trp (W)   2	  0.5%
Tyr (Y)  12	  2.9%
Val (V)  18	  4.3%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 73
Total number of positively charged residues (Arg + Lys): 51

Atomic composition:

Carbon      C	      2080
Hydrogen    H	      3341
Nitrogen    N	       585
Oxygen      O	       674
Sulfur      S	        10

Formula: C2080H3341N585O674S10
Total number of atoms: 6690

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    29005
Abs 0.1% (=1 g/l)   0.609, assuming all pairs of Cys residues form cystines


Ext. coefficient    28880
Abs 0.1% (=1 g/l)   0.606, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 56.18
This classifies the protein as unstable.



Aliphatic index: 92.29

Grand average of hydropathicity (GRAVY): -0.581