ProtParam
User-provided sequence:
10 20 30 40 50 60
MSGLRTVSAS SGNGKSYDSI MKILLIGDSG VGKSCLLVRF VEDKFNPSFI TTIGIDFKIK
70 80 90 100 110 120
TVDINGKKVK LQLWDTAGQE RFRTITTAYY RGAMGIILVY DVTDERTFTN IKQWFKTVNE
130 140 150 160 170 180
HANDEAQLLL VGNKSDMETR VVTADQGEAL AKELGIPFIE SSAKNDDNVN EIFFTLAKLI
190 200 210
QEKIDSNKLV GVGNGKEGNI SINSGSGNSS KSNCC
References and
documentation are available.
Number of amino acids: 215
Molecular weight: 23505.70
Theoretical pI: 6.61
Total number of negatively charged residues (Asp + Glu): 26
Total number of positively charged residues (Arg + Lys): 26
Atomic composition:
Carbon C 1034
Hydrogen H 1665
Nitrogen N 281
Oxygen O 328
Sulfur S 7
Formula: C
1034H
1665N
281O
328S
7
Total number of atoms: 3315
Extinction coefficients:
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 17085
Abs 0.1% (=1 g/l) 0.727, assuming all pairs of Cys residues form cystines
Ext. coefficient 16960
Abs 0.1% (=1 g/l) 0.722, assuming all Cys residues are reduced
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 23.59
This classifies the protein as stable.
Aliphatic index: 88.84
Grand average of hydropathicity (GRAVY): -0.226