ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSGNGAQGTK FRISLGLPVG AIMNCADNSG ARNLYIIAVK GSGSRLNRLP AASLGDMVMA 

        70         80         90        100        110        120 
TVKKGKPELR KKVMPAIVVR QAKSWRRRDG VFLYFEDNAG VIANPKGEMK GSAITGPVGK 

       130 
ECADLWPRVA SNSGVVV 

References and documentation are available.

Number of amino acids: 137

Molecular weight: 14472.93

Theoretical pI: 10.33

Amino acid composition: 
Ala (A)  15	 10.9%
Arg (R)  10	  7.3%
Asn (N)   8	  5.8%
Asp (D)   5	  3.6%
Cys (C)   2	  1.5%
Gln (Q)   2	  1.5%
Glu (E)   4	  2.9%
Gly (G)  17	 12.4%
His (H)   0	  0.0%
Ile (I)   7	  5.1%
Leu (L)   9	  6.6%
Lys (K)  11	  8.0%
Met (M)   6	  4.4%
Phe (F)   3	  2.2%
Pro (P)   7	  5.1%
Ser (S)  10	  7.3%
Thr (T)   3	  2.2%
Trp (W)   2	  1.5%
Tyr (Y)   2	  1.5%
Val (V)  14	 10.2%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 9
Total number of positively charged residues (Arg + Lys): 21

Atomic composition:

Carbon      C	       633
Hydrogen    H	      1048
Nitrogen    N	       190
Oxygen      O	       181
Sulfur      S	         8

Formula: C633H1048N190O181S8
Total number of atoms: 2060

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    14105
Abs 0.1% (=1 g/l)   0.975, assuming all pairs of Cys residues form cystines


Ext. coefficient    13980
Abs 0.1% (=1 g/l)   0.966, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 32.02
This classifies the protein as stable.



Aliphatic index: 86.13

Grand average of hydropathicity (GRAVY): -0.077