ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSGTFNDIRR RKKEEGSPTA GITERHENKS LSSIDKREQT LKPQLESCCP LATPFERRLQ 

        70         80         90        100        110        120 
TLAVAWHTSS FVLFSIFTLF AISTPALWVL AIPYMIYFFF DRSPATGEVV NRYSLRFRSL 

       130        140        150        160        170        180 
PIWKWYCDYF PISLIKTVNL KPTFTLSKNK RVNEKNYKIR LWPTKYSINL KSNSTIDYRN 

       190        200        210        220        230        240 
QECTGPTYLF GYHPHGIGAL GAFGAFATEG CNYSKIFPGI PISLMTLVTQ FHIPLYRDYL 

       250        260        270        280        290        300 
LALGISSVSR KNALRTLSKN QSICIVVGGA RESLLSSTNG TQLILNKRKG FIKLAIQTGN 

       310        320        330        340        350        360 
INLVPVFAFG EVDCYNVLST KKDSVLGKMQ LWFKENFGFT IPIFYARGLF NYDFGLLPFR 

       370        380        390        400        410 
APINVVVGRP IYVEKKITNP PDDVVNHFHD LYIAELKRLY YENREKYGVP DAELKIVG 

References and documentation are available.

Number of amino acids: 418

Molecular weight: 47711.35

Theoretical pI: 9.60

Amino acid composition: 
Ala (A)  21	  5.0%
Arg (R)  24	  5.7%
Asn (N)  24	  5.7%
Asp (D)  13	  3.1%
Cys (C)   7	  1.7%
Gln (Q)   9	  2.2%
Glu (E)  19	  4.5%
Gly (G)  26	  6.2%
His (H)   7	  1.7%
Ile (I)  32	  7.7%
Leu (L)  43	 10.3%
Lys (K)  29	  6.9%
Met (M)   4	  1.0%
Phe (F)  28	  6.7%
Pro (P)  24	  5.7%
Ser (S)  30	  7.2%
Thr (T)  27	  6.5%
Trp (W)   6	  1.4%
Tyr (Y)  21	  5.0%
Val (V)  24	  5.7%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 32
Total number of positively charged residues (Arg + Lys): 53

Atomic composition:

Carbon      C	      2199
Hydrogen    H	      3404
Nitrogen    N	       572
Oxygen      O	       594
Sulfur      S	        11

Formula: C2199H3404N572O594S11
Total number of atoms: 6780

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    64665
Abs 0.1% (=1 g/l)   1.355, assuming all pairs of Cys residues form cystines


Ext. coefficient    64290
Abs 0.1% (=1 g/l)   1.347, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 39.84
This classifies the protein as stable.



Aliphatic index: 91.65

Grand average of hydropathicity (GRAVY): -0.110