ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSHASPAAKP SNSKNPRVFF DVDIGGERVG RIVLELFADI VPKTAENFRA LCTGEKGTGS 

        70         80         90        100        110        120 
TTGKPLHFKG CPFHRIIKKF MIQGGDFSNQ NGTGGESIYG EKFEDENFHY KHDREGLLSM 

       130        140        150        160        170        180 
ANAGPNTNGS QFFITTVPTP HLDGKHVVFG QVIKGLGVAR TLENVEVNGE KPAKLCVIAE 

       190        200        210        220        230        240 
CGELKEGDDW GIFPKDGSGD SHPDFPEDAD IDLKDVDKIL LISEDLKNIG NTFFKSQNWE 

       250        260        270        280        290        300 
MAIKKYAKVL RYVDSSKAVI EKADRSRLQP IALSCVLNIG ACKLKMSNWQ GAIDSCLEAL 

       310        320        330        340        350        360 
EMDPSNTKAL YRKAQGWQGL KEYDQALADL KKAQEIAPGD KAIQAELLKV KQMIKAQKDK 

       370 
EKAVYAKMFA 

References and documentation are available.

Number of amino acids: 370

Molecular weight: 40742.55

Theoretical pI: 7.07

Amino acid composition: 
Ala (A)  32	  8.6%
Arg (R)  11	  3.0%
Asn (N)  17	  4.6%
Asp (D)  26	  7.0%
Cys (C)   7	  1.9%
Gln (Q)  14	  3.8%
Glu (E)  25	  6.8%
Gly (G)  33	  8.9%
His (H)   8	  2.2%
Ile (I)  23	  6.2%
Leu (L)  28	  7.6%
Lys (K)  40	 10.8%
Met (M)   8	  2.2%
Phe (F)  18	  4.9%
Pro (P)  16	  4.3%
Ser (S)  20	  5.4%
Thr (T)  13	  3.5%
Trp (W)   4	  1.1%
Tyr (Y)   7	  1.9%
Val (V)  20	  5.4%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 51
Total number of positively charged residues (Arg + Lys): 51

Atomic composition:

Carbon      C	      1811
Hydrogen    H	      2864
Nitrogen    N	       494
Oxygen      O	       544
Sulfur      S	        15

Formula: C1811H2864N494O544S15
Total number of atoms: 5728

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    32805
Abs 0.1% (=1 g/l)   0.805, assuming all pairs of Cys residues form cystines


Ext. coefficient    32430
Abs 0.1% (=1 g/l)   0.796, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 26.84
This classifies the protein as stable.



Aliphatic index: 78.08

Grand average of hydropathicity (GRAVY): -0.433