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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSHSLTSVFQ KIDSLKPQFF SRLTKAIQIP AVSSDESLRS KVFDKAKFIS EQLSQSGFHD

70 80 90 100 110 120
IKMVDLGIQP PPISTPNLSL PPVILSRFGS DPSKKTVLVY GHYDVQPAQL EDGWDTEPFK

130 140 150 160 170 180
LVIDEAKGIM KGRGVTDDTG PLLSWINVVD AFKASGQEFP VNLVTCFEGM EESGSLKLDE

190 200 210 220 230 240
LIKKEANGYF KGVDAVCISD NYWLGTKKPV LTYGLRGCNY YQTIIEGPSA DLHSGIFGGV

250 260 270 280 290 300
VAEPMIDLMQ VLGSLVDSKG KILIDGIDEM VAPLTEKEKA LYKDIEFSVE ELNAATGSKT

310 320 330 340 350 360
SLYDKKEDIL MHRWRYPSLS IHGVEGAFSA QGAKTVIPAK VFGKFSIRTV PDMDSEKLTS

370 380 390 400 410 420
LVQKHCDAKF KSLNSPNKCR TELIHDGAYW VSDPFNAQFT AAKKATKLVY GVDPDFTREG

430 440 450 460 470 480
GSIPITLTFQ DALNTSVLLL PMGRGDDGAH SINEKLDISN FVGGMKTMAA YLQYYSESPE


N


References and documentation are available.

Number of amino acids: 481 Molecular weight: 52871.38 Theoretical pI: 5.43
Amino acid composition: 
Ala (A) 29 6.0% Arg (R) 11 2.3% Asn (N) 14 2.9% Asp (D) 35 7.3% Cys (C) 5 1.0% Gln (Q) 16 3.3% Glu (E) 27 5.6% Gly (G) 38 7.9% His (H) 9 1.9% Ile (I) 30 6.2% Leu (L) 44 9.1% Lys (K) 40 8.3% Met (M) 12 2.5% Phe (F) 23 4.8% Pro (P) 26 5.4% Ser (S) 44 9.1% Thr (T) 25 5.2% Trp (W) 5 1.0% Tyr (Y) 15 3.1% Val (V) 33 6.9% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 62 Total number of positively charged residues (Arg + Lys): 51 Atomic composition: Carbon C 2377 Hydrogen H 3725 Nitrogen N 607 Oxygen O 720 Sulfur S 17 Formula: C2377H3725N607O720S17 Total number of atoms: 7446 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 50100 Abs 0.1% (=1 g/l) 0.948, assuming all pairs of Cys residues form cystines Ext. coefficient 49850 Abs 0.1% (=1 g/l) 0.943, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 32.62 This classifies the protein as stable. Aliphatic index: 85.93 Grand average of hydropathicity (GRAVY): -0.202