Home  |  Contact

ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSHSYASSSS SSSYRRMFGG PGYMTPPMSR GVFGRASTGG SGSSRVSSRV YEVSKSSTSS

70 80 90 100 110 120
PGFSGYRASS YSMPNLSAGY TRSYGGMGET LDFSLADALN QEFLHTRTNE KAELQHLNDR

130 140 150 160 170 180
FANYIEKVRM LEQQNQVLGV EVERLRGREP TRIADLYEDE MRELRREVEV VTNHRSRVEV

190 200 210 220 230 240
ERDNLADDLQ KLKLRLQEEI ALREEAENNL SAFRADVDAA TLARLDLERR IETLQEEIAF

250 260 270 280 290 300
LKKIHEEEIR ELQAQMQETQ VQIQMDMSKP DLTAALRDIR AQYEGIAAKN IAEAEDWYKS

310 320 330 340 350 360
KVSDLNQAVS KNNEALKQSK LETMEYRHQI QSYTCEIDSL KGSNESLMRQ MRDMEDRHGR

370 380 390 400 410 420
EAGALQDTIA RLEAEIANMK DEMARHLREY QDLLNVKMAL DVEIATYRKL LEGEESRIVM

430 440 450 460 470
PMQSYSTISF RETSPEHQQR ASEMHSKKTV LIKTIETRDG EVVSESTQHQ QDLM


References and documentation are available.

Number of amino acids: 474 Molecular weight: 54274.66 Theoretical pI: 5.36
Amino acid composition: 
Ala (A) 37 7.8% Arg (R) 43 9.1% Asn (N) 17 3.6% Asp (D) 25 5.3% Cys (C) 1 0.2% Gln (Q) 28 5.9% Glu (E) 55 11.6% Gly (G) 22 4.6% His (H) 11 2.3% Ile (I) 20 4.2% Leu (L) 42 8.9% Lys (K) 21 4.4% Met (M) 22 4.6% Phe (F) 9 1.9% Pro (P) 9 1.9% Ser (S) 48 10.1% Thr (T) 23 4.9% Trp (W) 1 0.2% Tyr (Y) 17 3.6% Val (V) 23 4.9% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 80 Total number of positively charged residues (Arg + Lys): 64 Atomic composition: Carbon C 2314 Hydrogen H 3734 Nitrogen N 692 Oxygen O 768 Sulfur S 23 Formula: C2314H3734N692O768S23 Total number of atoms: 7531 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 30830 Abs 0.1% (=1 g/l) 0.568, assuming all pairs of Cys residues form cystines Ext. coefficient 30830 Abs 0.1% (=1 g/l) 0.568, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 51.36 This classifies the protein as unstable. Aliphatic index: 72.89 Grand average of hydropathicity (GRAVY): -0.773