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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSICEQYYPE EPTKPTVKTE SIPGPESQKQ LKELGEVFDT RPAYFLADYE KSLGNYITDV

70 80 90 100 110 120
DGNTYLDLYA QISSIALGYN NPALIKAAQS PEMIRALVDR PALGNFPSKD LDKILKQILK

130 140 150 160 170 180
SAPKGQDHVW SGLSGADANE LAFKAAFIYY RAKQRGYDAD FSEKENLSVM DNDAPGAPHL

190 200 210 220 230 240
AVLSFKRAFH GRLFASGSTT CSKPIHKLDF PAFHWPHAEY PSYQYPLDEN SDANRKEDDH

250 260 270 280 290 300
CLAIVEELIK TWSIPVAALI IEPIQSEGGD NHASKYFLQK LRDITLKYNV VYIIDEVQTG

310 320 330 340 350 360
VGATGKLWCH EYADIQPPVD LVTFSKKFQS AGYFFHDPKF IPNKPYRQFN TWCGEPARMI

370 380 390 400 410 420
IAGAIGQEIS DKKLTEQCSR VGDYLFKKLE GLQKKYPENF QNLRGKGRGT FIAWDLPTGE

430 440 450 460 470
KRDLLLKKLK LNGCNVGGCA VHAVRLRPSL TFEEKHADIF IEALAKSVNE L


References and documentation are available.

Number of amino acids: 471 Molecular weight: 52946.24 Theoretical pI: 6.34
Amino acid composition: 
Ala (A) 41 8.7% Arg (R) 17 3.6% Asn (N) 19 4.0% Asp (D) 30 6.4% Cys (C) 8 1.7% Gln (Q) 19 4.0% Glu (E) 31 6.6% Gly (G) 31 6.6% His (H) 12 2.5% Ile (I) 29 6.2% Leu (L) 44 9.3% Lys (K) 40 8.5% Met (M) 4 0.8% Phe (F) 23 4.9% Pro (P) 29 6.2% Ser (S) 28 5.9% Thr (T) 18 3.8% Trp (W) 6 1.3% Tyr (Y) 22 4.7% Val (V) 20 4.2% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 61 Total number of positively charged residues (Arg + Lys): 57 Atomic composition: Carbon C 2399 Hydrogen H 3694 Nitrogen N 630 Oxygen O 700 Sulfur S 12 Formula: C2399H3694N630O700S12 Total number of atoms: 7435 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 66280 Abs 0.1% (=1 g/l) 1.252, assuming all pairs of Cys residues form cystines Ext. coefficient 65780 Abs 0.1% (=1 g/l) 1.242, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 33.53 This classifies the protein as stable. Aliphatic index: 81.46 Grand average of hydropathicity (GRAVY): -0.420