ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSIYLHIKFR LFLCIPDLPL RIHNQTFQEG LFCPFILHGF QNFVQRLALV KLDTVRGLFH 

        70         80         90        100        110        120 
FLCLLDHRLL HFLCRSCHWL VLVLLLLLLL LLLLLLLLVA LVQRFLVLLV LADARRVILV 

       130        140        150        160        170 
THAIFKRLGA IYACIVRVRT SIIMLFGILL GHSIITHLTV ERNHPVITNI S 

References and documentation are available.

Number of amino acids: 171

Molecular weight: 19825.43

Theoretical pI: 10.22

Amino acid composition: 
Ala (A)   7	  4.1%
Arg (R)  13	  7.6%
Asn (N)   4	  2.3%
Asp (D)   4	  2.3%
Cys (C)   6	  3.5%
Gln (Q)   5	  2.9%
Glu (E)   2	  1.2%
Gly (G)   6	  3.5%
His (H)  11	  6.4%
Ile (I)  16	  9.4%
Leu (L)  45	 26.3%
Lys (K)   3	  1.8%
Met (M)   2	  1.2%
Phe (F)  13	  7.6%
Pro (P)   4	  2.3%
Ser (S)   5	  2.9%
Thr (T)   7	  4.1%
Trp (W)   1	  0.6%
Tyr (Y)   2	  1.2%
Val (V)  15	  8.8%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 6
Total number of positively charged residues (Arg + Lys): 16

Atomic composition:

Carbon      C	       940
Hydrogen    H	      1523
Nitrogen    N	       245
Oxygen      O	       207
Sulfur      S	         8

Formula: C940H1523N245O207S8
Total number of atoms: 2923

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient     8855
Abs 0.1% (=1 g/l)   0.447, assuming all pairs of Cys residues form cystines


Ext. coefficient     8480
Abs 0.1% (=1 g/l)   0.428, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 37.92
This classifies the protein as stable.



Aliphatic index: 168.65

Grand average of hydropathicity (GRAVY): 1.139