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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSKAVGIDLG TTYSCVAHFS NDRVDIIAND QGNRTTPSFV GFTDTERLIG DAAKNQAAMN

70 80 90 100 110 120
PANTVFDAKR LIGRNFNDPE VQGDMKHFPF KLIDVDGKPQ IQVEFKGETK NFTPEQISSM

130 140 150 160 170 180
VLGKMKETAE SYLGAKVNDA VVTVPAYFND SQRQATKDAG TIAGLNVLRI INEPTAAAIA

190 200 210 220 230 240
YGLDKKGKEE HVLIFDLGGG TFDVSLLSIE DGIFEVKATA GDTHLGGEDF DNRLVNHFIQ

250 260 270 280 290 300
EFKRKNKKDL STNQRALRRL RTACERAKRT LSSSAQTSVE IDSLFEGIDF YTSITRARFE

310 320 330 340 350 360
ELCADLFRST LDPVEKVLRD AKLDKSQVDE IVLVGGSTRI PKVQKLVTDY FNGKEPNRSI

370 380 390 400 410 420
NPDEAVAYGA AVQAAILTGD ESSKTQDLLL LDVAPLSLGI ETAGGVMTKL IPRNSTIPTK

430 440 450 460 470 480
KSEVFSTYAD NQPGVLIQVF EGERAKTKDN NLLGKFELSG IPPAPRGVPQ IEVTFDVDSN

490 500 510 520 530 540
GILNVSAVEK GTGKSNKITI TNDKGRLSKE DIEKMVAEAE KFKEEDEKES QRIASKNQLE

550 560 570 580 590 600
SIAYSLKNTI SEAGDKLEQA DKDAVTKKAE ETIAWLDSNT TATKEEFDDQ LKELQEVANP

610 620 630
IMSKLYQAGG APEGAAPGGF PGGAPPAPEA EGPTVEEVD


References and documentation are available.

Number of amino acids: 639 Molecular weight: 69470.01 Theoretical pI: 4.94
Amino acid composition: 
Ala (A) 59 9.2% Arg (R) 26 4.1% Asn (N) 32 5.0% Asp (D) 48 7.5% Cys (C) 3 0.5% Gln (Q) 24 3.8% Glu (E) 53 8.3% Gly (G) 49 7.7% His (H) 5 0.8% Ile (I) 38 5.9% Leu (L) 48 7.5% Lys (K) 52 8.1% Met (M) 8 1.3% Phe (F) 28 4.4% Pro (P) 28 4.4% Ser (S) 39 6.1% Thr (T) 45 7.0% Trp (W) 1 0.2% Tyr (Y) 10 1.6% Val (V) 43 6.7% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 101 Total number of positively charged residues (Arg + Lys): 78 Atomic composition: Carbon C 3048 Hydrogen H 4888 Nitrogen N 836 Oxygen O 992 Sulfur S 11 Formula: C3048H4888N836O992S11 Total number of atoms: 9775 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 20525 Abs 0.1% (=1 g/l) 0.295, assuming all pairs of Cys residues form cystines Ext. coefficient 20400 Abs 0.1% (=1 g/l) 0.294, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 32.41 This classifies the protein as stable. Aliphatic index: 81.24 Grand average of hydropathicity (GRAVY): -0.446