ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSKGKVLLVL YEGGKHAEEQ EKLLGCIENE LGIRNFIEEQ GYELVTTIDK DPEPTSTVDR 

        70         80         90        100        110        120 
ELKDAEIVIT TPFFPAYISR NRIAEAPNLK LCVTAGVGSD HVDLEAANER KITVTEVTGS 

       130        140        150        160        170        180 
NVVSVAEHVM ATILVLIRNY NGGHQQAING EWDIAGVAKN EYDLEDKIIS TVGAGRIGYR 

       190        200        210        220        230        240 
VLERLVAFNP KKLLYYDYQE LPAEAINRLN EASKLFNGRG DIVQRVEKLE DMVAQSDVVT 

       250        260        270        280        290        300 
INCPLHKDSR GLFNKKLISH MKDGAYLVNT ARGAICVAED VAEAVKSGKL AGYGGDVWDK 

       310        320        330        340        350        360 
QPAPKDHPWR TMDNKDHVGN AMTVHISGTS LDAQKRYAQG VKNILNSYFS KKFDYRPQDI 

       370 
IVQNGSYATR AYGQKK 

References and documentation are available.

Number of amino acids: 376

Molecular weight: 41714.31

Theoretical pI: 6.04

Amino acid composition: 
Ala (A)  32	  8.5%
Arg (R)  18	  4.8%
Asn (N)  22	  5.9%
Asp (D)  24	  6.4%
Cys (C)   4	  1.1%
Gln (Q)  13	  3.5%
Glu (E)  28	  7.4%
Gly (G)  30	  8.0%
His (H)   9	  2.4%
Ile (I)  25	  6.6%
Leu (L)  29	  7.7%
Lys (K)  29	  7.7%
Met (M)   6	  1.6%
Phe (F)   8	  2.1%
Pro (P)  12	  3.2%
Ser (S)  17	  4.5%
Thr (T)  18	  4.8%
Trp (W)   3	  0.8%
Tyr (Y)  16	  4.3%
Val (V)  33	  8.8%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 52
Total number of positively charged residues (Arg + Lys): 47

Atomic composition:

Carbon      C	      1844
Hydrogen    H	      2937
Nitrogen    N	       515
Oxygen      O	       567
Sulfur      S	        10

Formula: C1844H2937N515O567S10
Total number of atoms: 5873

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    40590
Abs 0.1% (=1 g/l)   0.973, assuming all pairs of Cys residues form cystines


Ext. coefficient    40340
Abs 0.1% (=1 g/l)   0.967, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 26.27
This classifies the protein as stable.



Aliphatic index: 89.97

Grand average of hydropathicity (GRAVY): -0.387