ProtParam
User-provided sequence:
10 20 30 40 50 60
MSKHHPDLIM CKKQTGIAIG RVCDKCDGKC VICDSYVRPT TLVRICDECN YGSFQGKCVI
70 80 90 100 110
CGGQGVSDAY YCFACSREEK DRDGCPKIVN LGGSKIDLFY ERKKYGFKKR
References and
documentation are available.
Number of amino acids: 110
Molecular weight: 12351.38
Theoretical pI: 8.83
Total number of negatively charged residues (Asp + Glu): 13
Total number of positively charged residues (Arg + Lys): 20
Atomic composition:
Carbon C 532
Hydrogen H 851
Nitrogen N 153
Oxygen O 157
Sulfur S 14
Formula: C
532H
851N
153O
157S
14
Total number of atoms: 1707
Extinction coefficients:
This protein does not contain any Trp residues. Experience shows that
this could result in more than 10% error in the computed extinction coefficient.
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 9690
Abs 0.1% (=1 g/l) 0.785, assuming all pairs of Cys residues form cystines
Ext. coefficient 8940
Abs 0.1% (=1 g/l) 0.724, assuming all Cys residues are reduced
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 37.54
This classifies the protein as stable.
Aliphatic index: 63.73
Grand average of hydropathicity (GRAVY): -0.408