ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSKIDSVLII GGSGFLGLHL IQQFFDINPK PDIHIFDVRD LPEKLSKQFT FNVDDIKFHK 

        70         80         90        100        110        120 
GDLTSPDDME NAINESKANV VVHCASPMHG QNPDIYDIVN VKGTRNVIDM CKKCGVNILV 

       130        140        150        160        170        180 
YTSSAGVIFN GQDVHNADET WPIPEVPMDA YNETKAIAED MVLKANDPSS DFYTVALRPA 

       190        200        210        220        230        240 
GIFGPGDRQL VPGLRQVAKL GQSKFQIGDN NNLFDWTYAG NVADAHVLAA QKLLDPKTRT 

       250        260        270        280        290        300 
AVSGETFFIT NDTPTYFWAL ARTVWKADGH IDKHVIVLKR PVAICAGYLS EWVSKMLGKE 

       310        320        330        340 
PGLTPFRVKI VCAYRYHNIA KAKKLLGYTP RVGIEEGINK TLAWMDEGL 

References and documentation are available.

Number of amino acids: 349

Molecular weight: 38706.37

Theoretical pI: 6.21

Amino acid composition: 
Ala (A)  27	  7.7%
Arg (R)  11	  3.2%
Asn (N)  20	  5.7%
Asp (D)  28	  8.0%
Cys (C)   5	  1.4%
Gln (Q)  10	  2.9%
Glu (E)  13	  3.7%
Gly (G)  26	  7.4%
His (H)  10	  2.9%
Ile (I)  26	  7.4%
Leu (L)  26	  7.4%
Lys (K)  26	  7.4%
Met (M)   8	  2.3%
Phe (F)  16	  4.6%
Pro (P)  19	  5.4%
Ser (S)  15	  4.3%
Thr (T)  18	  5.2%
Trp (W)   6	  1.7%
Tyr (Y)  10	  2.9%
Val (V)  29	  8.3%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 41
Total number of positively charged residues (Arg + Lys): 37

Atomic composition:

Carbon      C	      1746
Hydrogen    H	      2718
Nitrogen    N	       464
Oxygen      O	       505
Sulfur      S	        13

Formula: C1746H2718N464O505S13
Total number of atoms: 5446

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    48150
Abs 0.1% (=1 g/l)   1.244, assuming all pairs of Cys residues form cystines


Ext. coefficient    47900
Abs 0.1% (=1 g/l)   1.238, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 33.31
This classifies the protein as stable.



Aliphatic index: 89.94

Grand average of hydropathicity (GRAVY): -0.162