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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSKQQIGVVG MAVMGRNLAL NIESRGYTVS IFNRSREKTE EVIAENPGKK LVPYYTVKEF

70 80 90 100 110 120
VESLETPRRI LLMVKAGAGT DAAIDSLKPY LDKGDIIIDG GNTFFQDTIR RNRELSAEGF

130 140 150 160 170 180
NFIGTGVSGG EEGALKGPSI MPGGQKEAYE LVAPILTKIA AVAEDGEPCV TYIGADGAGH

190 200 210 220 230 240
YVKMVHNGIE YGDMQLIAEA YSLLKGGLNL TNEELAQTFT EWNNGELSSY LIDITKDIFT

250 260 270 280 290 300
KKDEDGNYLV DVILDEAANK GTGKWTSQSA LDLGEPLSLI TESVFARYIS SLKDQRVAAS

310 320 330 340 350 360
KVLSGPQAQP AGDKAEFIEK VRRALYLGKI VSYAQGFSQL RAASEEYNWD LNYGEIAKIF

370 380 390 400 410 420
RAGCIIRAQF LQKITDAYAE NPQIANLLLA PYFKQIADDY QQALRDVVAY AVQNGIPVPT

430 440 450 460
FSAAVAYYDS YRAAVLPANL IQAQRDYFGA HTYKRIDKEG VFHTEWLD


References and documentation are available.

Number of amino acids: 468 Molecular weight: 51481.31 Theoretical pI: 5.04
Amino acid composition: 
Ala (A) 51 10.9% Arg (R) 20 4.3% Asn (N) 20 4.3% Asp (D) 27 5.8% Cys (C) 2 0.4% Gln (Q) 21 4.5% Glu (E) 34 7.3% Gly (G) 41 8.8% His (H) 4 0.9% Ile (I) 35 7.5% Leu (L) 40 8.5% Lys (K) 28 6.0% Met (M) 7 1.5% Phe (F) 17 3.6% Pro (P) 16 3.4% Ser (S) 25 5.3% Thr (T) 22 4.7% Trp (W) 4 0.9% Tyr (Y) 25 5.3% Val (V) 29 6.2% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 61 Total number of positively charged residues (Arg + Lys): 48 Atomic composition: Carbon C 2311 Hydrogen H 3613 Nitrogen N 609 Oxygen O 704 Sulfur S 9 Formula: C2311H3613N609O704S9 Total number of atoms: 7246 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 59375 Abs 0.1% (=1 g/l) 1.153, assuming all pairs of Cys residues form cystines Ext. coefficient 59250 Abs 0.1% (=1 g/l) 1.151, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 35.98 This classifies the protein as stable. Aliphatic index: 91.37 Grand average of hydropathicity (GRAVY): -0.200