ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSKRNTPPLR SSGINTIQIN AAREMHAQTV RARRMPMPTS GITTPSVQPT AAPATPPRHI 

        70         80         90        100        110        120 
CNNPNNPQCL HCGSVIIPSP RATLPLEDNP SISINDWTIS SRKKPILNSQ ELDIWENEKL 

       130        140        150        160        170        180 
KGLTLPEMIF GNNYIRIENS KQHWSIEFNA LDALKEVQLQ DSGIRVAYSN DWINSKKRQN 

       190        200        210        220        230        240 
STNGAQRFTN DVNDDSLNII HKYDWTYTTR YKGTESSPES KFRLDNDQKL PLDKLAVHDK 

       250        260        270        280        290        300 
ILFYDDMILF EDELADNGIS ILNVKIRVMN ERLLLLSRFF LRVDDVLVRV YDTRIYVEFD 

       310        320        330        340        350 
ENVVIRESKE FEGKYQDVLA KHRLSQSHDP KAALRDSNWV AQNTPMIKRQ CEIIQF 

References and documentation are available.

Number of amino acids: 356

Molecular weight: 41019.54

Theoretical pI: 7.69

Amino acid composition: 
Ala (A)  18	  5.1%
Arg (R)  25	  7.0%
Asn (N)  29	  8.1%
Asp (D)  25	  7.0%
Cys (C)   4	  1.1%
Gln (Q)  16	  4.5%
Glu (E)  20	  5.6%
Gly (G)  10	  2.8%
His (H)   8	  2.2%
Ile (I)  30	  8.4%
Leu (L)  30	  8.4%
Lys (K)  21	  5.9%
Met (M)   8	  2.2%
Phe (F)  11	  3.1%
Pro (P)  21	  5.9%
Ser (S)  28	  7.9%
Thr (T)  19	  5.3%
Trp (W)   6	  1.7%
Tyr (Y)   9	  2.5%
Val (V)  18	  5.1%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 45
Total number of positively charged residues (Arg + Lys): 46

Atomic composition:

Carbon      C	      1807
Hydrogen    H	      2871
Nitrogen    N	       519
Oxygen      O	       548
Sulfur      S	        12

Formula: C1807H2871N519O548S12
Total number of atoms: 5757

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    46660
Abs 0.1% (=1 g/l)   1.138, assuming all pairs of Cys residues form cystines


Ext. coefficient    46410
Abs 0.1% (=1 g/l)   1.131, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 47.48
This classifies the protein as unstable.



Aliphatic index: 85.45

Grand average of hydropathicity (GRAVY): -0.597