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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSKSQIESTW SSLLQELEII WKEVGETETE REKILIEIEE ECREVYNRKI EKVKEEKIRI

70 80 90 100 110 120
KQEIADSEAR VIDICSVMEE PPILGRHHQS DQQSGNGRSL KDELVKILQK LEEMEKRKSE

130 140 150 160 170 180
RKIQFIQVID DIRCVREEIN GESDDETCSS DFSADESDLS LRKLEELHRE LYTLQEQKRN

190 200 210 220 230 240
RVKQIQDNIR TLESLCSVLG LNFRETVTKI HPSLVDTEGS RSISNETLDK LASSVQQWHE

250 260 270 280 290 300
TKIQRMQELQ DLVTTMLEFW NLMDTPAEEQ QKFMDVSCNI AATVSEITKP NSLSIDLLEE

310 320 330 340 350 360
VKAELCRLEE LKWSKMKELV LKKRSELEEI CRRTHIVLEE EDIAVENVIK AIESGDVNPE

370 380 390 400 410 420
NILEQIEYRA GKVKEEALSR KEILEKADKW LNACEEENWL EEYNQDENRY NAGKGSHLIL

430 440 450 460 470 480
KRAEKARALV NKLPAMVEAL ASKITIWESE KEYEFLFDGN RLLSMLEEYT ELREEKEQER

490 500 510 520 530 540
RRKRDLKKHQ GQVTSEQDKG SVTKPQSAKK GLKVSTNKRF VSSPHTPQTD SPHSAKSNQS


FSTPLSRHG


References and documentation are available.

Number of amino acids: 549 Molecular weight: 63869.11 Theoretical pI: 5.20
Amino acid composition: 
Ala (A) 23 4.2% Arg (R) 36 6.6% Asn (N) 22 4.0% Asp (D) 26 4.7% Cys (C) 9 1.6% Gln (Q) 29 5.3% Glu (E) 85 15.5% Gly (G) 16 2.9% His (H) 11 2.0% Ile (I) 38 6.9% Leu (L) 54 9.8% Lys (K) 51 9.3% Met (M) 10 1.8% Phe (F) 9 1.6% Pro (P) 12 2.2% Ser (S) 49 8.9% Thr (T) 25 4.6% Trp (W) 8 1.5% Tyr (Y) 7 1.3% Val (V) 29 5.3% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 111 Total number of positively charged residues (Arg + Lys): 87 Atomic composition: Carbon C 2764 Hydrogen H 4511 Nitrogen N 789 Oxygen O 904 Sulfur S 19 Formula: C2764H4511N789O904S19 Total number of atoms: 8987 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 54930 Abs 0.1% (=1 g/l) 0.860, assuming all pairs of Cys residues form cystines Ext. coefficient 54430 Abs 0.1% (=1 g/l) 0.852, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 64.91 This classifies the protein as unstable. Aliphatic index: 84.86 Grand average of hydropathicity (GRAVY): -0.830