ProtParam
User-provided sequence:
10 20 30 40 50 60
MSLAVSLRRA LLVLLTGAIF ILTVLYWNQG VTKAQAYNEA LERPHSHHDA SGFPIPVEKS
70 80 90 100 110 120
WTYKCENDRC MRVGHHGKSA KRVSFISCSM TCGDVNIWPH PTQKFLLSSQ THSFSVEDVQ
130 140 150 160 170 180
LHVDTAHREV RKQLQLAFDW FLKDLRLIQR LDYVGSSSEP TVSESSSKSR HHADLEPAAT
190 200 210 220 230 240
LFGATFGVKK AGDLTSVQVK ISVLKSGDLN FSLDNDETYQ LSTQTEGHRL QVEIIANSYF
250 260 270 280 290 300
GARHGLSTLQ QLIWFDDEDH LLHTYANSKV KDAPKFRYRG LMLDTSRHFF SVESIKRTIV
310 320 330 340 350 360
GMGLAKMNRF HWHLTDAQSF PYISRYYPEL AVHGAYSESE TYSEQDVREV AEFAKIYGVQ
370 380 390 400 410 420
VIPEIDAPAH AGNGWDWGPK RGMGELAMCI NQQPWSFYCG EPPCGQLNPK NNYTYLILQR
430 440 450 460 470 480
IYEELLQHTG PTDFFHLGGD EVNLDCWAQY FNDTDLRGLW CDFMLQAMAR LKLANNGVAP
490 500 510 520 530 540
KHVAVWSSAL TNTKCLPNSQ FTVQVWGGST WQENYDLLDN GYNVIFSHVD AWYLDCGFGS
550 560 570 580 590 600
WRATGDAACA PYRTWQNVYK HRPWERMRLD KKRKKQVLGG EVCMWTEQVD ENQLDNRLWP
610 620 630 640 650 660
RTAALAERLW TDPSDDHDMD IVPPDVFRRI SLFRNRLVEL GIRAEALFPK YCAQNPGECI
References and
documentation are available.
Number of amino acids: 660
Molecular weight: 75486.33
Theoretical pI: 6.30
Total number of negatively charged residues (Asp + Glu): 77
Total number of positively charged residues (Arg + Lys): 68
Atomic composition:
Carbon C 3381
Hydrogen H 5135
Nitrogen N 937
Oxygen O 980
Sulfur S 28
Formula: C
3381H
5135N
937O
980S
28
Total number of atoms: 10461
Extinction coefficients:
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 153625
Abs 0.1% (=1 g/l) 2.035, assuming all pairs of Cys residues form cystines
Ext. coefficient 152750
Abs 0.1% (=1 g/l) 2.024, assuming all Cys residues are reduced
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 32.99
This classifies the protein as stable.
Aliphatic index: 77.58
Grand average of hydropathicity (GRAVY): -0.407