ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSLGIPLSQL IVESPKPLSS GITGLDEILN LGFQARSIYE IFGPPGIGKT NFGIQLVCNS 

        70         80         90        100        110        120 
LEGIQQSEIN DDKILWIETF QEMPINILRE RFQKFKIVEE NVKRVRITKF GQLLYFFQNL 

       130        140        150        160        170        180 
FKLSQSVRYK LVIIDGFSQL VCDHLCTLSK RGGGMIDKTI HELKCRHLIL IFTVMTKYTH 

       190        200        210        220        230        240 
STGSTIIVLN DCMNTAFQSN EFESLEEYYE ILDDGSNFFV NSNNERRKNN VHILKSALVA 

       250        260        270        280        290        300 
NIAMGSKDST WEVFLRDRIG LFRDWNEQVD ETVFVKSKRV KASSSQSNEG CTTIKEMRIN 

       310        320        330        340        350        360 
KRNFENLRIA IVFNLHGEDR KREGRNLKRS RSSDDRNYIV KFDFDKATGQ LRDIIDLKPD 

       370        380        390        400 
TANIASFPTL STSSSSCSQV FNNIDSNDNP LPNAEGKEEI IYDSEG 

References and documentation are available.

Number of amino acids: 406

Molecular weight: 46349.72

Theoretical pI: 6.37

Amino acid composition: 
Ala (A)  11	  2.7%
Arg (R)  24	  5.9%
Asn (N)  31	  7.6%
Asp (D)  24	  5.9%
Cys (C)   7	  1.7%
Gln (Q)  16	  3.9%
Glu (E)  29	  7.1%
Gly (G)  24	  5.9%
His (H)   6	  1.5%
Ile (I)  39	  9.6%
Leu (L)  36	  8.9%
Lys (K)  27	  6.7%
Met (M)   7	  1.7%
Phe (F)  25	  6.2%
Pro (P)  10	  2.5%
Ser (S)  38	  9.4%
Thr (T)  20	  4.9%
Trp (W)   3	  0.7%
Tyr (Y)   8	  2.0%
Val (V)  21	  5.2%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 53
Total number of positively charged residues (Arg + Lys): 51

Atomic composition:

Carbon      C	      2053
Hydrogen    H	      3259
Nitrogen    N	       567
Oxygen      O	       626
Sulfur      S	        14

Formula: C2053H3259N567O626S14
Total number of atoms: 6519

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    28795
Abs 0.1% (=1 g/l)   0.621, assuming all pairs of Cys residues form cystines


Ext. coefficient    28420
Abs 0.1% (=1 g/l)   0.613, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 52.15
This classifies the protein as unstable.



Aliphatic index: 89.75

Grand average of hydropathicity (GRAVY): -0.356