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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSLISKSLAR IECSPFFYPR ASEITTGKRI TSPQIRLYTA AAVGGKTGNG ERKQRAKAPA

70 80 90 100 110 120
KTPEAVTPVK PLEIASVTAT TENELPRPNE IAYESEVANW VNLIGFVDQP VQFEASSDGK

130 140 150 160 170 180
FWAGTVISQR SASDSSGFWI PIIFEGDLAK TAARYVSKDD QIHVSGKLFI DSPPPNMTYA

190 200 210 220 230 240
QANVQVLVQN LNFIQPMSPS PSPFMVMSSS EKEESGIKKQ PARAKQDIVI DEASDSWNHL

250 260 270 280 290 300
IENPKEWWDH RENKVNGLVK PRHPDFKSKD SSFSLWLNKA PNWVLPKLEG LEFDVLVPKA

310 320 330 340 350 360
RVVKQLKGEE SWKDLVQNPD KWWDNRIDKR NAKAPDFKHK ETGEALWLNE SPTWVLPKLP

370
PVKKKQESIV F


References and documentation are available.

Number of amino acids: 371 Molecular weight: 41729.49 Theoretical pI: 8.84
Amino acid composition: 
Ala (A) 29 7.8% Arg (R) 15 4.0% Asn (N) 19 5.1% Asp (D) 19 5.1% Cys (C) 1 0.3% Gln (Q) 15 4.0% Glu (E) 27 7.3% Gly (G) 16 4.3% His (H) 5 1.3% Ile (I) 21 5.7% Leu (L) 24 6.5% Lys (K) 35 9.4% Met (M) 5 1.3% Phe (F) 15 4.0% Pro (P) 31 8.4% Ser (S) 34 9.2% Thr (T) 15 4.0% Trp (W) 13 3.5% Tyr (Y) 5 1.3% Val (V) 27 7.3% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 46 Total number of positively charged residues (Arg + Lys): 50 Atomic composition: Carbon C 1884 Hydrogen H 2938 Nitrogen N 508 Oxygen O 552 Sulfur S 6 Formula: C1884H2938N508O552S6 Total number of atoms: 5888 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 78950 Abs 0.1% (=1 g/l) 1.892, assuming all pairs of Cys residues form cystines Ext. coefficient 78950 Abs 0.1% (=1 g/l) 1.892, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 52.09 This classifies the protein as unstable. Aliphatic index: 76.23 Grand average of hydropathicity (GRAVY): -0.557