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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSLLLPTNLQ QYPSSSSFPS STPILSPPPS TAFSVIVPRR RCLRLVTSCV STVQSSVATN

70 80 90 100 110 120
GSSPAPAPAA VVVERDQIRL GLPSKGRMAA DAIDLLKDCQ LFVKQVNPRQ YVAQIPQLPN

130 140 150 160 170 180
TEVWFQRPKD IVRKLLSGDL DLGIVGLDTL SEYGQENEDL IIVHEALNFG DCHLSIAIPN

190 200 210 220 230 240
YGIFENINSL KELAQMPQWS EERPLRLATG FTYLGPKFMK ENGIKHVVFS TADGALEAAP

250 260 270 280 290 300
AMGIADAILD LVSSGITLKE NNLKEIEGGV VLESQAALVA SRRALNERKG ALNTVHEILE

310 320 330 340 350 360
RLEAHLKADG QFTVVANMRG NSAQEVAERV LSQPSLSGLQ GPTISPVYCT QNGKVSVDYY

370 380 390 400 410
AIVICVPKKA LYDSVKQLRA AGGSGVLVSP LTYIFDEDTP RWGQLLRNLG I


References and documentation are available.

Number of amino acids: 411 Molecular weight: 44556.16 Theoretical pI: 6.04
Amino acid composition: 
Ala (A) 35 8.5% Arg (R) 21 5.1% Asn (N) 18 4.4% Asp (D) 18 4.4% Cys (C) 6 1.5% Gln (Q) 21 5.1% Glu (E) 23 5.6% Gly (G) 28 6.8% His (H) 5 1.2% Ile (I) 24 5.8% Leu (L) 49 11.9% Lys (K) 17 4.1% Met (M) 6 1.5% Phe (F) 11 2.7% Pro (P) 27 6.6% Ser (S) 36 8.8% Thr (T) 18 4.4% Trp (W) 3 0.7% Tyr (Y) 10 2.4% Val (V) 35 8.5% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 41 Total number of positively charged residues (Arg + Lys): 38 Atomic composition: Carbon C 1981 Hydrogen H 3195 Nitrogen N 543 Oxygen O 597 Sulfur S 12 Formula: C1981H3195N543O597S12 Total number of atoms: 6328 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 31775 Abs 0.1% (=1 g/l) 0.713, assuming all pairs of Cys residues form cystines Ext. coefficient 31400 Abs 0.1% (=1 g/l) 0.705, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 46.92 This classifies the protein as unstable. Aliphatic index: 102.48 Grand average of hydropathicity (GRAVY): -0.017