ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSLNIHIKSG QDKWEVNVAP ESTVLQFKEA INKANGIPVA NQRLIYSGKI LKDDQTVESY 

        70         80         90        100        110        120 
HIQDGHSVHL VKSQPKPQTA SAAGANNATA TGAAAGTGAT PNMSSGQSAG FNPLADLTSA 

       130        140        150        160        170        180 
RYAGYLNMPS ADMFGPDGGA LNNDSNNQDE LLRMMENPIF QSQMNEMLSN PQMLDFMIQS 

       190        200        210        220        230        240 
NPQLQAMGPQ ARQMLQSPMF RQMLTNPDMI RQSMQFARMM DPNAGMGSAG GAASAFPAPG 

       250        260        270        280        290        300 
GDAPEEGSNT NTTSSSNTGN NAGTNAGTNA GANTAANPFA SLLNPALNPF ANAGNAASTG 

       310        320        330        340        350        360 
MPAFDPALLA SMFQPPVQAS QAEDTRPPEE RYEHQLRQLN DMGFFDFDRN VAALRRSGGS 

       370 
VQGALDSLLN GDV 

References and documentation are available.

Number of amino acids: 373

Molecular weight: 39345.62

Theoretical pI: 4.78

Amino acid composition: 
Ala (A)  50	 13.4%
Arg (R)  13	  3.5%
Asn (N)  36	  9.7%
Asp (D)  20	  5.4%
Cys (C)   0	  0.0%
Gln (Q)  27	  7.2%
Glu (E)  13	  3.5%
Gly (G)  33	  8.8%
His (H)   5	  1.3%
Ile (I)  10	  2.7%
Leu (L)  27	  7.2%
Lys (K)   8	  2.1%
Met (M)  22	  5.9%
Phe (F)  15	  4.0%
Pro (P)  27	  7.2%
Ser (S)  32	  8.6%
Thr (T)  18	  4.8%
Trp (W)   1	  0.3%
Tyr (Y)   5	  1.3%
Val (V)  11	  2.9%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 33
Total number of positively charged residues (Arg + Lys): 21

Atomic composition:

Carbon      C	      1677
Hydrogen    H	      2630
Nitrogen    N	       494
Oxygen      O	       558
Sulfur      S	        22

Formula: C1677H2630N494O558S22
Total number of atoms: 5381

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    12950
Abs 0.1% (=1 g/l)   0.329

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 47.08
This classifies the protein as unstable.



Aliphatic index: 60.64

Grand average of hydropathicity (GRAVY): -0.472