ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSLNNITFCV SQDLDVPLKV KIKSLEGHKP LLKPSQKILN PELMLIGSNV FPSSDLIVSL 

        70         80         90        100        110        120 
QVFDKERNRN LTLPIYTPYI PFRNSRTWDY WLTLPIRIKQ LTFSSHLRII LWEYNGSKQI 

       130        140        150        160        170        180 
PFFNLETSIF NLKDCTLKRG FESLKFRYDV IDHCEVVTDN KDQENLNKYF QGEFTRLPWL 

       190        200        210        220        230        240 
DEITISKLRK QRENRTWPQG TFVLNLEFPM LELPVVFIER EIMNTQMNIP TLKNNPGLST 

       250        260        270        280        290        300 
DLREPNRNDP QIKISLGDKY HSTLKFYDPD QPNNDPIEEK YRRLERASKN ANLDKQVKPD 

       310        320        330        340        350        360 
IKKRDYLNKI INYPPGTKLT AHEKGSIWKY RYYLMNNKKA LTKLLQSTNL REESERVEVL 

       370        380        390        400        410        420 
ELMDSWAEID IDDALELLGS TFKNLSVRSY AVNRLKKASD KELELYLLQL VEAVCFENLS 

       430        440        450        460        470        480 
TFSDKSNSEF TIVDAVSSQK LSGDSMLLST SHANQKLLKS ISSESETSGT ESLPIVISPL 

       490        500        510        520        530        540 
AEFLIRRALV NPRLGSFFYW YLKSESEDKP YLDQILSSFW SRLDKKSRNI LNDQVRLINV 

       550        560        570        580        590        600 
LRECCETIKR LKDTTAKKME LLVHLLETKV RPLVKVRPIA LPLDPDVLIC DVCPETSKVF 

       610        620        630        640        650        660 
KSSLSPLKIT FKTTLNQPYH LMFKVGDDLR QDQLVVQIIS LMNELLKNEN VDLKLTPYKI 

       670        680        690        700        710        720 
LATGPQEGAI EFIPNDTLAS ILSKYHGILG YLKLHYPDEN ATLGVQGWVL DNFVKSCAGY 

       730        740        750        760        770        780 
CVITYILGVG DRHLDNLLVT PDGHFFHADF GYILGQDPKP FPPLMKLPPQ IIEAFGGAES 

       790        800        810        820        830        840 
SNYDKFRSYC FVAYSILRRN AGLILNLFEL MKTSNIPDIR IDPNGAILRV RERFNLNMSE 

       850        860        870 
EDATVHFQNL INDSVNALLP IVIDHLHNLA QYWRT 

References and documentation are available.

Number of amino acids: 875

Molecular weight: 100921.40

Theoretical pI: 7.84

Amino acid composition: 
Ala (A)  29	  3.3%
Arg (R)  44	  5.0%
Asn (N)  58	  6.6%
Asp (D)  54	  6.2%
Cys (C)  11	  1.3%
Gln (Q)  29	  3.3%
Glu (E)  54	  6.2%
Gly (G)  31	  3.5%
His (H)  16	  1.8%
Ile (I)  61	  7.0%
Leu (L) 121	 13.8%
Lys (K)  66	  7.5%
Met (M)  14	  1.6%
Phe (F)  39	  4.5%
Pro (P)  49	  5.6%
Ser (S)  66	  7.5%
Thr (T)  44	  5.0%
Trp (W)  11	  1.3%
Tyr (Y)  31	  3.5%
Val (V)  47	  5.4%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 108
Total number of positively charged residues (Arg + Lys): 110

Atomic composition:

Carbon      C	      4568
Hydrogen    H	      7227
Nitrogen    N	      1203
Oxygen      O	      1320
Sulfur      S	        25

Formula: C4568H7227N1203O1320S25
Total number of atoms: 14343

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient   107315
Abs 0.1% (=1 g/l)   1.063, assuming all pairs of Cys residues form cystines


Ext. coefficient   106690
Abs 0.1% (=1 g/l)   1.057, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 40.58
This classifies the protein as unstable.



Aliphatic index: 100.01

Grand average of hydropathicity (GRAVY): -0.305