ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSLNRGSKML LRALTPQILR RGKADYGKTV CNLKINKATK VLVQGFTGKQ ATFHSEESIK 

        70         80         90        100        110        120 
YGTNIVGGVN PKKGGTEHLG KPVFKSVAEA VEKAKPDATV IFIPPPSAAE GICAAIESEI 

       130        140        150        160        170        180 
GLIVAITEGI PQADMVRISQ MLNCQEKSRL LGPNCPGIIS PDQCKIGIMP GDIHKRGVVG 

       190        200        210        220        230        240 
IVSRSGTLTY ESVHQTTNVG LGQALCVGLG GDPFNGTSFI DALKVFLSDK EIKGIVMIGE 

       250        260        270        280        290        300 
IGGSAEEEAA DFLKEKNTGC EAKPVVGFIA GQTAPPGRRM GHAGAIISGG KGAAKDKVAA 

       310        320        330        340 
LEKAGVRMTA NPCHLGSTLL EEMIRLKLVP KPNKKKAQAG KK 

References and documentation are available.

Number of amino acids: 342

Molecular weight: 35870.89

Theoretical pI: 9.45

Amino acid composition: 
Ala (A)  32	  9.4%
Arg (R)  12	  3.5%
Asn (N)  12	  3.5%
Asp (D)  10	  2.9%
Cys (C)   8	  2.3%
Gln (Q)  11	  3.2%
Glu (E)  21	  6.1%
Gly (G)  43	 12.6%
His (H)   6	  1.8%
Ile (I)  28	  8.2%
Leu (L)  25	  7.3%
Lys (K)  34	  9.9%
Met (M)   9	  2.6%
Phe (F)   9	  2.6%
Pro (P)  19	  5.6%
Ser (S)  18	  5.3%
Thr (T)  18	  5.3%
Trp (W)   0	  0.0%
Tyr (Y)   3	  0.9%
Val (V)  24	  7.0%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 31
Total number of positively charged residues (Arg + Lys): 46

Atomic composition:

Carbon      C	      1578
Hydrogen    H	      2619
Nitrogen    N	       447
Oxygen      O	       467
Sulfur      S	        17

Formula: C1578H2619N447O467S17
Total number of atoms: 5128

Extinction coefficients:

This protein does not contain any Trp residues. Experience shows that
this could result in more than 10% error in the computed extinction coefficient.

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient     4970
Abs 0.1% (=1 g/l)   0.139, assuming all pairs of Cys residues form cystines


Ext. coefficient     4470
Abs 0.1% (=1 g/l)   0.125, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 30.24
This classifies the protein as stable.



Aliphatic index: 90.15

Grand average of hydropathicity (GRAVY): -0.092