ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSLPAHLQQT FSPEEIQFIV ENEPIKIFPR ITTRQKIRGD DRGTGNHTRW QLITTDDKAL 

        70         80         90        100        110        120 
NNMVAMRSTE VVLWIALLLK QQSKCSIVAP QWLTTKELDR KIQYEKTHPD RFSELPWNWL 

       130        140        150        160        170        180 
VLARILFNKA KDDFHDPIHE LRGKIQDLRE IRQIKVLKGL KYLNESHLQL DNLSLLEINE 

       190        200        210 
LRPFITEIMD KLREIHTASL TAGTENDEEE FNI 

References and documentation are available.

Number of amino acids: 213

Molecular weight: 25060.81

Theoretical pI: 6.18

Amino acid composition: 
Ala (A)   9	  4.2%
Arg (R)  14	  6.6%
Asn (N)  11	  5.2%
Asp (D)  13	  6.1%
Cys (C)   1	  0.5%
Gln (Q)  12	  5.6%
Glu (E)  19	  8.9%
Gly (G)   6	  2.8%
His (H)   7	  3.3%
Ile (I)  20	  9.4%
Leu (L)  27	 12.7%
Lys (K)  15	  7.0%
Met (M)   4	  1.9%
Phe (F)   8	  3.8%
Pro (P)   9	  4.2%
Ser (S)   9	  4.2%
Thr (T)  15	  7.0%
Trp (W)   5	  2.3%
Tyr (Y)   2	  0.9%
Val (V)   7	  3.3%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 32
Total number of positively charged residues (Arg + Lys): 29

Atomic composition:

Carbon      C	      1123
Hydrogen    H	      1796
Nitrogen    N	       312
Oxygen      O	       327
Sulfur      S	         5

Formula: C1123H1796N312O327S5
Total number of atoms: 3563

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    30480
Abs 0.1% (=1 g/l)   1.216, assuming all pairs of Cys residues form cystines


Ext. coefficient    30480
Abs 0.1% (=1 g/l)   1.216, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 49.49
This classifies the protein as unstable.



Aliphatic index: 99.81

Grand average of hydropathicity (GRAVY): -0.504