ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSLRLPQNPN AGLFKQGYNS YSNADGQIIK SIAAIRELHQ MCLTSMGPCG RNKIIVNHLG 

        70         80         90        100        110        120 
KIIITNDAAT MLRELDIVHP AVKVLVMATE QQKIDMGDGT NLVMILAGEL LNVSEKLISM 

       130        140        150        160        170        180 
GLSAVEIIQG YNMARKFTLK ELDEMVVGEI TDKNDKNELL KMIKPVISSK KYGSEDILSE 

       190        200        210        220        230        240 
LVSEAVSHVL PVAQQAGEIP YFNVDSIRVV KIMGGSLSNS TVIKGMVFNR EPEGHVKSLS 

       250        260        270        280        290        300 
EDKKHKVAVF TCPLDIANTE TKGTVLLHNA QEMLDFSKGE EKQIDAMMKE IADMGVECIV 

       310        320        330        340        350        360 
AGAGVGELAL HYLNRYGILV LKVPSKFELR RLCRVCGATP LPRLGAPTPE ELGLVETVKT 

       370        380        390        400        410        420 
MEIGGDRVTV FKQEQGEISR TSTIILRGAT QNNLDDIERA IDDGVAAVKG LMKPSGGKLL 

       430        440        450        460        470        480 
PGAGATEIEL ISRITKYGER TPGLLQLAIK QFAVAFEVVP RTLAETAGLD VNEVLPNLYA 

       490        500        510        520        530        540 
AHNVTEPGAV KTDHLYKGVD IDGESDEGVK DIREENIYDM LATKKFAINV ATEAATTVLS 

       550        560 
IDQIIMAKKA GGPRAPQGPR PGNWDQED 

References and documentation are available.

Number of amino acids: 568

Molecular weight: 61662.28

Theoretical pI: 5.51

Amino acid composition: 
Ala (A)  46	  8.1%
Arg (R)  22	  3.9%
Asn (N)  26	  4.6%
Asp (D)  30	  5.3%
Cys (C)   6	  1.1%
Gln (Q)  19	  3.3%
Glu (E)  45	  7.9%
Gly (G)  49	  8.6%
His (H)  10	  1.8%
Ile (I)  45	  7.9%
Leu (L)  55	  9.7%
Lys (K)  41	  7.2%
Met (M)  21	  3.7%
Phe (F)  11	  1.9%
Pro (P)  24	  4.2%
Ser (S)  28	  4.9%
Thr (T)  31	  5.5%
Trp (W)   1	  0.2%
Tyr (Y)  11	  1.9%
Val (V)  47	  8.3%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 75
Total number of positively charged residues (Arg + Lys): 63

Atomic composition:

Carbon      C	      2713
Hydrogen    H	      4453
Nitrogen    N	       741
Oxygen      O	       834
Sulfur      S	        27

Formula: C2713H4453N741O834S27
Total number of atoms: 8768

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    22265
Abs 0.1% (=1 g/l)   0.361, assuming all pairs of Cys residues form cystines


Ext. coefficient    21890
Abs 0.1% (=1 g/l)   0.355, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 32.65
This classifies the protein as stable.



Aliphatic index: 100.76

Grand average of hydropathicity (GRAVY): -0.089