ProtParam
User-provided sequence:
10 20 30 40 50 60
MSLRPCLTPS SMQYSDIYIH TPHPHPHPHP HTPTHTHPHT PTPTPHPHPH TPHPHTTPTP
70 80 90 100 110 120
TPHHTHTPHT TLSNLSLNLP SHYPTSPLVT LPHSTIPLPT TIHLSTYYYH PPPIITVTLQ
130 140 150
LPISNSTTIT LLLPYHPPCP THCTVVLPSI LKR
References and
documentation are available.
Number of amino acids: 153
Molecular weight: 17080.57
Theoretical pI: 8.56
Total number of negatively charged residues (Asp + Glu): 1
Total number of positively charged residues (Arg + Lys): 3
Atomic composition:
Carbon C 780
Hydrogen H 1183
Nitrogen N 213
Oxygen O 211
Sulfur S 5
Formula: C
780H
1183N
213O
211S
5
Total number of atoms: 2392
Extinction coefficients:
This protein does not contain any Trp residues. Experience shows that
this could result in more than 10% error in the computed extinction coefficient.
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 10555
Abs 0.1% (=1 g/l) 0.618, assuming all pairs of Cys residues form cystines
Ext. coefficient 10430
Abs 0.1% (=1 g/l) 0.611, assuming all Cys residues are reduced
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 43.11
This classifies the protein as unstable.
Aliphatic index: 73.86
Grand average of hydropathicity (GRAVY): -0.484