ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSLRRGGLMS YNQRRIARWY FGGLASSMAA MVTHPIDLIK VLIQTQAEKL SVFQTTRKIV 

        70         80         90        100        110        120 
KEQGPLAMYN GISASMLRQY TYTLARFGIY SVGSGAMDTS TMAGKTCLAA IAGGIGGFVG 

       130        140        150        160        170        180 
APADLINVRL QNDVKLPPEK RRNYKHAIDG LVRITREEGW KNLFNGSSMI ALRGAFMTVG 

       190        200        210        220        230        240 
QIAFYEQSKS QMIKLGMPDY MGTYILASMI SSVVATTLTQ PIDVVKTRRM NAAPGEYSGL 

       250        260        270        280        290        300 
GDVFVKTSKE GPLAFFKGYV PSLSRLLPHT VLLFLGLEYL RTHFGYLPEP KQTGAFYRYD 


DVDD 

References and documentation are available.

Number of amino acids: 304

Molecular weight: 33592.07

Theoretical pI: 9.72

Amino acid composition: 
Ala (A)  25	  8.2%
Arg (R)  19	  6.2%
Asn (N)   8	  2.6%
Asp (D)  12	  3.9%
Cys (C)   1	  0.3%
Gln (Q)  12	  3.9%
Glu (E)  10	  3.3%
Gly (G)  30	  9.9%
His (H)   4	  1.3%
Ile (I)  18	  5.9%
Leu (L)  30	  9.9%
Lys (K)  16	  5.3%
Met (M)  15	  4.9%
Phe (F)  13	  4.3%
Pro (P)  13	  4.3%
Ser (S)  21	  6.9%
Thr (T)  20	  6.6%
Trp (W)   2	  0.7%
Tyr (Y)  16	  5.3%
Val (V)  19	  6.2%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 22
Total number of positively charged residues (Arg + Lys): 35

Atomic composition:

Carbon      C	      1511
Hydrogen    H	      2395
Nitrogen    N	       407
Oxygen      O	       426
Sulfur      S	        16

Formula: C1511H2395N407O426S16
Total number of atoms: 4755

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    34840
Abs 0.1% (=1 g/l)   1.037, assuming all pairs of Cys residues form cystines


Ext. coefficient    34840
Abs 0.1% (=1 g/l)   1.037, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 40.00
This classifies the protein as stable.



Aliphatic index: 87.93

Grand average of hydropathicity (GRAVY): -0.022