ProtParam
User-provided sequence:
10 20 30 40 50 60
MSLRTPKRSR TSDEQEQEQE QEQVQNPDTH VNNEHQQRPG PTTLLSTPVR LKNGFGTPSP
70 80 90 100 110 120
PSPPGITKSI TKSRRRPSTT SLQGIFMSPV NKRRVGITAH GRVYDHNDDG HESESEDDEN
130 140 150 160 170 180
EEENENQKKY DGHVSMPLLP PTTPKSRRSE VFLSPSPRLR SPPTAARRST GERPIREISH
190 200 210 220 230 240
TLRTRLNYAL VKLQNGWTDK TLPELETELA PAVQTPPRRY HNRFPDSADA GTSAHTAFLQ
250 260 270 280 290
ALGGHPPREE ATAVETLMLL SSPTKKQQHR PVPATSAGEP TDETEPESDT EVETS
References and
documentation are available.
Number of amino acids: 295
Molecular weight: 32901.20
Theoretical pI: 6.28
Total number of negatively charged residues (Asp + Glu): 42
Total number of positively charged residues (Arg + Lys): 38
Atomic composition:
Carbon C 1405
Hydrogen H 2251
Nitrogen N 435
Oxygen O 471
Sulfur S 4
Formula: C
1405H
2251N
435O
471S
4
Total number of atoms: 4566
Extinction coefficients:
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 11460
Abs 0.1% (=1 g/l) 0.348
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 85.41
This classifies the protein as unstable.
Aliphatic index: 53.56
Grand average of hydropathicity (GRAVY): -1.153