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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSLSLGAAIY IALKPIFKIY TIMLVGYLVA KFDIVSMENA KGISNMVVNA ILPCLTFNKI

70 80 90 100 110 120
VSNISWRDIK EIGVIILSAF ILFVLGATGA LFTTFATTVP KKFFWGLIFA GFFPNISDLP

130 140 150 160 170 180
IAYIQSMGNG SIFTAEEADK GVAYSCIFLF IQSFLMMNFG MWRVVGLDFR DTKEPDSENI

190 200 210 220 230 240
TPSVSPAIDD RKLTEITKLP NITRPTNAYQ SEDARSNSDL SCNSITTNEM TPQAFYEGFT

250 260 270 280 290 300
GYIKPYKESN GASHKFESDL PHAEIYRVSS TYSSPGALEF SRIDGSSLSY SRISKNSDGR

310 320 330 340 350 360
SYRRKRKADM NELISKYSAA EKIRQGELDL SRPLSLTEEV GSRNASIGNV HTGYTDESSI

370 380 390 400 410 420
EEENCTNMAT DGRGSLSFFI ERHNLKWLQY FIINCLRPAS LGAILGIICA LIPWVKACFV

430 440 450 460 470 480
TTYVHVHKAP DGEPVLNFLM DFTEYIGNAC VPLGLLLLGG TLARLEIKSL PPGFIKSALL

490 500 510 520 530 540
MTCFRLIVIP IIGVLWVNKL YSIDWLDTGI GKFDMILTWS MPSATAQVYF TAFYTPACGD

550 560 570
HIQMNCLSVL FVMQYAILFI TVAFVVTYTL KVDLKV


References and documentation are available.

Number of amino acids: 576 Molecular weight: 64032.31 Theoretical pI: 6.42
Amino acid composition: 
Ala (A) 41 7.1% Arg (R) 21 3.6% Asn (N) 27 4.7% Asp (D) 25 4.3% Cys (C) 11 1.9% Gln (Q) 9 1.6% Glu (E) 27 4.7% Gly (G) 37 6.4% His (H) 7 1.2% Ile (I) 55 9.5% Leu (L) 56 9.7% Lys (K) 29 5.0% Met (M) 17 3.0% Phe (F) 36 6.2% Pro (P) 25 4.3% Ser (S) 52 9.0% Thr (T) 37 6.4% Trp (W) 8 1.4% Tyr (Y) 23 4.0% Val (V) 33 5.7% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 52 Total number of positively charged residues (Arg + Lys): 50 Atomic composition: Carbon C 2924 Hydrogen H 4546 Nitrogen N 726 Oxygen O 829 Sulfur S 28 Formula: C2924H4546N726O829S28 Total number of atoms: 9053 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 78895 Abs 0.1% (=1 g/l) 1.232, assuming all pairs of Cys residues form cystines Ext. coefficient 78270 Abs 0.1% (=1 g/l) 1.222, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 40.07 This classifies the protein as unstable. Aliphatic index: 98.89 Grand average of hydropathicity (GRAVY): 0.236