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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSLSQVSPLP HIKDVVLGDT VGQGAFACVK NAHLQMDPSI ILAVKFIHVP TCKKMGLSDK

70 80 90 100 110 120
DITKEVVLQS KCSKHPNVLR LIDCNVSKEY MWIILEMADG GDLFDKIEPD VGVDSDVAQF

130 140 150 160 170 180
YFQQLVSAIN YLHVECGVAH RDIKPENILL DKNGNLKLAD FGLASQFRRK DGTLRVSMDQ

190 200 210 220 230 240
RGSPPYMAPE VLYSEEGYYA DRTDIWSIGI LLFVLLTGQT PWELPSLENE DFVFFIENDG

250 260 270 280 290 300
NLNWGPWSKI EFTHLNLLRK ILQPDPNKRV TLKALKLHPW VLRRASFSGD DGLCNDPELL

310 320 330 340 350 360
AKKLFSHLKV SLSNENYLKF TQDTNSNNRY ISTQPIGNEL AELEHDSMHF QTVSNTQRAF

370 380 390 400 410 420
TSYDSNTNYN SGTGMTQEAK WTQFISYDIA ALQFHSDEND CNELVKRHLQ FNPNKLTKFY

430 440 450 460 470 480
TLQPMDVLLP ILEKALNLSQ IRVKPDLFAN FERLCELLGY DNVFPLIINI KTKSNGGYQL

490 500 510 520
CGSISIIKIE EELKSVGFER KTGDPLEWRR LFKKISTICR DIILIPN


References and documentation are available.

Number of amino acids: 527 Molecular weight: 60016.79 Theoretical pI: 5.86
Amino acid composition: 
Ala (A) 22 4.2% Arg (R) 20 3.8% Asn (N) 34 6.5% Asp (D) 36 6.8% Cys (C) 10 1.9% Gln (Q) 22 4.2% Glu (E) 30 5.7% Gly (G) 28 5.3% His (H) 13 2.5% Ile (I) 36 6.8% Leu (L) 64 12.1% Lys (K) 37 7.0% Met (M) 10 1.9% Phe (F) 26 4.9% Pro (P) 25 4.7% Ser (S) 37 7.0% Thr (T) 24 4.6% Trp (W) 8 1.5% Tyr (Y) 15 2.8% Val (V) 30 5.7% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 66 Total number of positively charged residues (Arg + Lys): 57 Atomic composition: Carbon C 2701 Hydrogen H 4228 Nitrogen N 714 Oxygen O 792 Sulfur S 20 Formula: C2701H4228N714O792S20 Total number of atoms: 8455 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 66975 Abs 0.1% (=1 g/l) 1.116, assuming all pairs of Cys residues form cystines Ext. coefficient 66350 Abs 0.1% (=1 g/l) 1.106, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 38.25 This classifies the protein as stable. Aliphatic index: 94.69 Grand average of hydropathicity (GRAVY): -0.265