ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSLTAQFSPP VTGITRSLRD TKPSLSNLRV FPVYTEIRTM TTSNLRKSAC FVAKAIEQRR 

        70         80         90        100        110        120 
DTAGSESESE ATPSPAEESG SGEDKEVEIS AIGAEIKAAM EQRKTAEEEK GKNEFLSGVA 

       130        140        150        160        170 
EEVKEIEWPA FQKVLGTTGV VLGVIAGSSV VLLTVNFLLA ELSDRVFIGR GVQDFFS 

References and documentation are available.

Number of amino acids: 177

Molecular weight: 19120.60

Theoretical pI: 4.91

Amino acid composition: 
Ala (A)  16	  9.0%
Arg (R)  10	  5.6%
Asn (N)   4	  2.3%
Asp (D)   5	  2.8%
Cys (C)   1	  0.6%
Gln (Q)   5	  2.8%
Glu (E)  21	 11.9%
Gly (G)  13	  7.3%
His (H)   0	  0.0%
Ile (I)   9	  5.1%
Leu (L)  13	  7.3%
Lys (K)  10	  5.6%
Met (M)   3	  1.7%
Phe (F)   9	  5.1%
Pro (P)   7	  4.0%
Ser (S)  19	 10.7%
Thr (T)  14	  7.9%
Trp (W)   1	  0.6%
Tyr (Y)   1	  0.6%
Val (V)  16	  9.0%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 26
Total number of positively charged residues (Arg + Lys): 20

Atomic composition:

Carbon      C	       839
Hydrogen    H	      1357
Nitrogen    N	       227
Oxygen      O	       273
Sulfur      S	         4

Formula: C839H1357N227O273S4
Total number of atoms: 2700

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient     6990
Abs 0.1% (=1 g/l)   0.366, assuming all pairs of Cys residues form cystines


Ext. coefficient     6990
Abs 0.1% (=1 g/l)   0.366, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 54.79
This classifies the protein as unstable.



Aliphatic index: 83.73

Grand average of hydropathicity (GRAVY): -0.174