ProtParam
User-provided sequence:
10 20 30 40 50 60
MSLVKLANTC AHLQNCSKVR VALTSIPYTK LQLQFAYNLY QQGFLSSLQK GSTMGPDKDF
70 80 90 100 110 120
VEVTPDNIST RRLWVGLKYR DNKPVLSSCK LISKPNSRIH LPMEDMKKLC SGVTIRNIKP
130 140 150
LQPGELILVR AHNNIMDINE AISKKLDGEV LCRVK
References and
documentation are available.
Number of amino acids: 155
Molecular weight: 17470.57
Theoretical pI: 9.65
Total number of negatively charged residues (Asp + Glu): 12
Total number of positively charged residues (Arg + Lys): 23
Atomic composition:
Carbon C 772
Hydrogen H 1278
Nitrogen N 218
Oxygen O 221
Sulfur S 10
Formula: C
772H
1278N
218O
221S
10
Total number of atoms: 2499
Extinction coefficients:
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 11710
Abs 0.1% (=1 g/l) 0.670, assuming all pairs of Cys residues form cystines
Ext. coefficient 11460
Abs 0.1% (=1 g/l) 0.656, assuming all Cys residues are reduced
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 38.39
This classifies the protein as stable.
Aliphatic index: 99.94
Grand average of hydropathicity (GRAVY): -0.221