ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSMLMAVKTT SLCCSSLNLT ASPTFRRNPR AARLVNPTAR IQTRFHRLIE EQGIVLMPGC 

        70         80         90        100        110        120 
YDALSAAIVQ QTGFSAGFIS GYALSASLLG KPDFGLLTPP EMAATARSVC ASAPNIPIIA 

       130        140        150        160        170        180 
DADTGGGNAL NIQRTVKDLI AAGAAGCFLE DQAWPKKCGH MRGKQVIPAE EHAAKIASAR 

       190        200        210        220        230        240 
DAIGDSDFFL VARTDVRATS AKSGLEDAIA RVNLYMEAGA DASFVEAPRD DDELKEIGKR 

       250        260        270        280        290        300 
TKGYRVCNMI EGGVTPLHTP DELKEMGFHL IVHPLTALYA STRALVDVLK TLKENGSTRD 

       310        320        330 
HLQKMATFEE FNSLVDLDSW FELEARYSNL RNALGTTKS 

References and documentation are available.

Number of amino acids: 339

Molecular weight: 36565.80

Theoretical pI: 6.40

Amino acid composition: 
Ala (A)  45	 13.3%
Arg (R)  21	  6.2%
Asn (N)  12	  3.5%
Asp (D)  20	  5.9%
Cys (C)   7	  2.1%
Gln (Q)   8	  2.4%
Glu (E)  19	  5.6%
Gly (G)  24	  7.1%
His (H)   7	  2.1%
Ile (I)  17	  5.0%
Leu (L)  34	 10.0%
Lys (K)  16	  4.7%
Met (M)  10	  2.9%
Phe (F)  13	  3.8%
Pro (P)  15	  4.4%
Ser (S)  23	  6.8%
Thr (T)  23	  6.8%
Trp (W)   2	  0.6%
Tyr (Y)   6	  1.8%
Val (V)  17	  5.0%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 39
Total number of positively charged residues (Arg + Lys): 37

Atomic composition:

Carbon      C	      1601
Hydrogen    H	      2572
Nitrogen    N	       454
Oxygen      O	       490
Sulfur      S	        17

Formula: C1601H2572N454O490S17
Total number of atoms: 5134

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    20315
Abs 0.1% (=1 g/l)   0.556, assuming all pairs of Cys residues form cystines


Ext. coefficient    19940
Abs 0.1% (=1 g/l)   0.545, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 31.38
This classifies the protein as stable.



Aliphatic index: 86.49

Grand average of hydropathicity (GRAVY): -0.096