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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSMLSRRLFS TSRLAAFSKI KVKQPVVELD GDEMTRIIWD KIKKKLILPY LDVDLKYYDL

70 80 90 100 110 120
SVESRDATSD KITQDAAEAI KKYGVGIKCA TITPDEARVK EFNLHKMWKS PNGTIRNILG

130 140 150 160 170 180
GTVFREPIVI PRIPRLVPRW EKPIIIGRHA HGDQYKATDT LIPGPGSLEL VYKPSDPTTA

190 200 210 220 230 240
QPQTLKVYDY KGSGVAMAMY NTDESIEGFA HSSFKLAIDK KLNLFLSTKN TILKKYDGRF

250 260 270 280 290 300
KDIFQEVYEA QYKSKFEQLG IHYEHRLIDD MVAQMIKSKG GFIMALKNYD GDVQSDIVAQ

310 320 330 340 350 360
GFGSLGLMTS ILVTPDGKTF ESEAAHGTVT RHYRKYQKGE ETSTNSIASI FAWSRGLLKR

370 380 390 400 410 420
GELDNTPALC KFANILESAT LNTVQQDGIM TKDLALACGN NERSAYVTTE EFLDAVEKRL


QKEIKSIE


References and documentation are available.

Number of amino acids: 428 Molecular weight: 48190.38 Theoretical pI: 8.84
Amino acid composition: 
Ala (A) 30 7.0% Arg (R) 20 4.7% Asn (N) 13 3.0% Asp (D) 28 6.5% Cys (C) 3 0.7% Gln (Q) 15 3.5% Glu (E) 27 6.3% Gly (G) 28 6.5% His (H) 8 1.9% Ile (I) 34 7.9% Leu (L) 37 8.6% Lys (K) 41 9.6% Met (M) 11 2.6% Phe (F) 16 3.7% Pro (P) 16 3.7% Ser (S) 29 6.8% Thr (T) 29 6.8% Trp (W) 4 0.9% Tyr (Y) 17 4.0% Val (V) 22 5.1% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 55 Total number of positively charged residues (Arg + Lys): 61 Atomic composition: Carbon C 2158 Hydrogen H 3441 Nitrogen N 577 Oxygen O 642 Sulfur S 14 Formula: C2158H3441N577O642S14 Total number of atoms: 6832 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 47455 Abs 0.1% (=1 g/l) 0.985, assuming all pairs of Cys residues form cystines Ext. coefficient 47330 Abs 0.1% (=1 g/l) 0.982, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 33.13 This classifies the protein as stable. Aliphatic index: 86.61 Grand average of hydropathicity (GRAVY): -0.371